Vaccination in patients with kidney failure: lessons from COVID-19

N Babel, C Hugo, TH Westhoff - Nature Reviews Nephrology, 2022‏ - nature.com
Infection is the second leading cause of death in patients with chronic kidney disease (CKD).
Adequate humoral (antibody) and cellular (T cell-driven) immunity are required to minimize …

[HTML][HTML] Erythropoietin (EPO) as a key regulator of erythropoiesis, bone remodeling and endothelial transdifferentiation of multipotent mesenchymal stem cells (MSCs) …

AS Tsiftsoglou - Cells, 2021‏ - mdpi.com
Human erythropoietin (EPO) is an N-linked glycoprotein consisting of 166 aa that is
produced in the kidney during the adult life and acts both as a peptide hormone and …

Clinical application of cytokines in cancer immunotherapy

Y Qiu, M Su, L Liu, Y Tang, Y Pan… - Drug design, development …, 2021‏ - Taylor & Francis
Cytokines are key components of the immune system and play pivotal roles in anticancer
immune response. Cytokines as either therapeutic agents or targets hold clinical promise for …

Erythropoietin and its derivatives: from tissue protection to immune regulation

B Peng, G Kong, C Yang, Y Ming - Cell death & disease, 2020‏ - nature.com
Erythropoietin (EPO) is an evolutionarily conserved hormone well documented for its
erythropoietic role via binding the homodimeric EPO receptor (EPOR) 2. In past decades …

[HTML][HTML] The efficacy of COVID-19 vaccines in chronic kidney disease and kidney transplantation patients: a narrative review

YC Hou, KC Lu, KL Kuo - Vaccines, 2021‏ - mdpi.com
The SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) pandemic has posed a
huge threat to global health because of its rapid spread and various mutant variants. Critical …

The relationship between serum erythropoietin, hepcidin, and haptoglobin levels with disease severity and other biochemical values in patients with COVID‐19

S Yağcı, E Serin, Ö Acicbe, Mİ Zeren… - … Journal of Laboratory …, 2021‏ - Wiley Online Library
Introduction Studies have shown that iron metabolism is affected by coronavirus disease 19
(COVID‐19), which has spread worldwide and has become a global health problem. Our …

Multi-omics identify falling LRRC15 as a COVID-19 severity marker and persistent pro-thrombotic signals in convalescence

JS Gisby, NB Buang, A Papadaki, CL Clarke… - Nature …, 2022‏ - nature.com
Patients with end-stage kidney disease (ESKD) are at high risk of severe COVID-19. Here,
we perform longitudinal blood sampling of ESKD haemodialysis patients with COVID-19 …

Immunology of kidney disease

O Foresto-Neto, L Menezes-Silva… - Annual Review of …, 2024‏ - annualreviews.org
The immune system and the kidneys are closely related. Immune components mediate
acute kidney disease and are crucial to the progression of chronic kidney disease. Beyond …

Erythropoietin as a neuroprotective drug for newborn infants: ten years after the first use

S Perrone, C Lembo, F Gironi, C Petrolini, T Catalucci… - Antioxidants, 2022‏ - mdpi.com
Protective strategies against perinatal brain injury represent a major challenge for modern
neonatology. Erythropoietin (Epo) enhances endogenous mechanisms of repair and …

[HTML][HTML] STAT5 as a key protein of erythropoietin signalization

Z Tóthová, J Tomc, N Debeljak, P Solár - International journal of …, 2021‏ - mdpi.com
Erythropoietin (EPO) acts on multiple tissues through its receptor EPOR, a member of a
cytokine class I receptor superfamily with pleiotropic effects. The interaction of EPO and …