Global extraintestinal pathogenic Escherichia coli (ExPEC) lineages
AR Manges, HM Geum, A Guo, TJ Edens… - Clinical microbiology …, 2019 - Am Soc Microbiol
SUMMARY Extraintestinal pathogenic Escherichia coli (ExPEC) strains are responsible for a
majority of human extraintestinal infections globally, resulting in enormous direct medical …
majority of human extraintestinal infections globally, resulting in enormous direct medical …
Escherichia coli ST131, an intriguing clonal group
MH Nicolas-Chanoine, X Bertrand… - Clinical microbiology …, 2014 - Am Soc Microbiol
In 2008, a previously unknown Escherichia coli clonal group, sequence type 131 (ST131),
was identified on three continents. Today, ST131 is the predominant E. coli lineage among …
was identified on three continents. Today, ST131 is the predominant E. coli lineage among …
Global dissemination of a multidrug resistant Escherichia coli clone
NK Petty, NL Ben Zakour… - Proceedings of the …, 2014 - National Acad Sciences
Escherichia coli sequence type 131 (ST131) is a globally disseminated, multidrug resistant
(MDR) clone responsible for a high proportion of urinary tract and bloodstream infections …
(MDR) clone responsible for a high proportion of urinary tract and bloodstream infections …
Metagenomic assembly reveals hosts of antibiotic resistance genes and the shared resistome in pig, chicken, and human feces
The risk associated with antibiotic resistance disseminating from animal and human feces is
an urgent public issue. In the present study, we sought to establish a pipeline for annotating …
an urgent public issue. In the present study, we sought to establish a pipeline for annotating …
Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist
CN Spaulding, RD Klein, S Ruer, AL Kau, HL Schreiber… - Nature, 2017 - nature.com
Urinary tract infections (UTIs) caused by uropathogenic Escherichia coli (UPEC) affect 150
million people annually,. Despite effective antibiotic therapy, 30–50% of patients experience …
million people annually,. Despite effective antibiotic therapy, 30–50% of patients experience …
Host–pathogen checkpoints and population bottlenecks in persistent and intracellular uropathogenic Escherichia coli bladder infection
Bladder infections affect millions of people yearly, and recurrent symptomatic infections
(cystitis) are very common. The rapid increase in infections caused by multidrug-resistant …
(cystitis) are very common. The rapid increase in infections caused by multidrug-resistant …
Systematic longitudinal survey of invasive Escherichia coli in England demonstrates a stable population structure only transiently disturbed by the emergence of …
Escherichia coli associated with urinary tract infections and bacteremia has been intensively
investigated, including recent work focusing on the virulent, globally disseminated, multidrug …
investigated, including recent work focusing on the virulent, globally disseminated, multidrug …
Drug and vaccine development for the treatment and prevention of urinary tract infections
VP O'brien, TJ Hannan, HV Nielsen… - Urinary Tract Infections …, 2017 - Wiley Online Library
Urinary tract infections (UTI) are one of the most common bacterial infections, with roughly
eleven‐million cases reported in the US each year that cost an estimated $5 billion annually …
eleven‐million cases reported in the US each year that cost an estimated $5 billion annually …
Sequential acquisition of virulence and fluoroquinolone resistance has shaped the evolution of Escherichia coli ST131
Escherichia coli ST131 is the most frequently isolated fluoroquinolone-resistant (FQR) E. coli
clone worldwide and a major cause of urinary tract and bloodstream infections. Although …
clone worldwide and a major cause of urinary tract and bloodstream infections. Although …
Fourteen years in resistance
DM Livermore - International journal of antimicrobial agents, 2012 - Elsevier
Resistance trends have changed greatly over the 14 years (1997–2011) whilst I was
Director of the UK Antibiotic Resistance Monitoring and Reference Laboratory (ARMRL) …
Director of the UK Antibiotic Resistance Monitoring and Reference Laboratory (ARMRL) …