Microbiome and human health: current understanding, engineering, and enabling technologies
The human microbiome is composed of a collection of dynamic microbial communities that
inhabit various anatomical locations in the body. Accordingly, the coevolution of the …
inhabit various anatomical locations in the body. Accordingly, the coevolution of the …
Microbiome-based therapeutics
Symbiotic microorganisms inhabiting the gastrointestinal tract promote health by decreasing
susceptibility to infection and enhancing resistance to a range of diseases. In this Review …
susceptibility to infection and enhancing resistance to a range of diseases. In this Review …
Gut microbiome correlates of response and toxicity following anti-CD19 CAR T cell therapy
M Smith, A Dai, G Ghilardi, KV Amelsberg, SM Devlin… - Nature medicine, 2022 - nature.com
Anti-CD19 chimeric antigen receptor (CAR) T cell therapy has led to unprecedented
responses in patients with high-risk hematologic malignancies. However, up to 60% of …
responses in patients with high-risk hematologic malignancies. However, up to 60% of …
Cross-feeding in the gut microbiome: ecology and mechanisms
Microbial communities are shaped by positive and negative interactions ranging from
competition to mutualism. In the context of the mammalian gut and its microbial inhabitants …
competition to mutualism. In the context of the mammalian gut and its microbial inhabitants …
Effects of early-life antibiotics on the develo** infant gut microbiome and resistome: a randomized trial
M Reyman, MA Van Houten, RL Watson… - Nature …, 2022 - nature.com
Broad-spectrum antibiotics for suspected early-onset neonatal sepsis (sEONS) may have
pronounced effects on gut microbiome development and selection of antimicrobial …
pronounced effects on gut microbiome development and selection of antimicrobial …
[HTML][HTML] Design, construction, and in vivo augmentation of a complex gut microbiome
Efforts to model the human gut microbiome in mice have led to important insights into the
mechanisms of host-microbe interactions. However, the model communities studied to date …
mechanisms of host-microbe interactions. However, the model communities studied to date …
Unravelling the collateral damage of antibiotics on gut bacteria
Antibiotics are used to fight pathogens but also target commensal bacteria, disturbing the
composition of gut microbiota and causing dysbiosis and disease. Despite this well-known …
composition of gut microbiota and causing dysbiosis and disease. Despite this well-known …
Human gut microbiota/microbiome in health and diseases: a review
EZ Gomaa - Antonie Van Leeuwenhoek, 2020 - Springer
The human gut microbiota has received considerable interest in the recent years and our
knowledge of the inhabitant species and their potential applications is increased particularly …
knowledge of the inhabitant species and their potential applications is increased particularly …
Microbiota succession throughout life from the cradle to the grave
Associations between age and the human microbiota are robust and reproducible. The
microbial composition at several body sites can predict human chronological age relatively …
microbial composition at several body sites can predict human chronological age relatively …
[HTML][HTML] Antibiotics as major disruptors of gut microbiota
J Ramirez, F Guarner, L Bustos Fernandez… - Frontiers in cellular …, 2020 - frontiersin.org
Advances in culture-independent research techniques have led to an increased
understanding of the gut microbiota and the role it plays in health and disease. The intestine …
understanding of the gut microbiota and the role it plays in health and disease. The intestine …