Modulation of the TLR-mediated inflammatory response by the endogenous human host defense peptide LL-37
The sole human cathelicidin peptide, LL-37, has been demonstrated to protect animals
against endotoxemia/sepsis. Low, physiological concentrations of LL-37 (≤ 1 μg/ml) were …
against endotoxemia/sepsis. Low, physiological concentrations of LL-37 (≤ 1 μg/ml) were …
An anti-infective peptide that selectively modulates the innate immune response
MG Scott, E Dullaghan, N Mookherjee, N Glavas… - Nature …, 2007 - nature.com
We show that an innate defense–regulator peptide (IDR-1) was protective in mouse models
of infection with important Gram-positive and Gram-negative pathogens, including methicillin …
of infection with important Gram-positive and Gram-negative pathogens, including methicillin …
The Commensal Streptococcus salivarius K12 Downregulates the Innate Immune Responses of Human Epithelial Cells and Promotes Host-Microbe Homeostasis
C Cosseau, DA Devine, E Dullaghan… - Infection and …, 2008 - Am Soc Microbiol
Streptococcus salivarius is an early colonizer of human oral and nasopharyngeal epithelia,
and strain K12 has reported probiotic effects. An emerging paradigm indicates that …
and strain K12 has reported probiotic effects. An emerging paradigm indicates that …
InnateDB: facilitating systems‐level analyses of the mammalian innate immune response
Although considerable progress has been made in dissecting the signaling pathways
involved in the innate immune response, it is now apparent that this response can no longer …
involved in the innate immune response, it is now apparent that this response can no longer …
EXPANDER – an integrative program suite for microarray data analysis
Background Gene expression microarrays are a prominent experimental tool in functional
genomics which has opened the opportunity for gaining global, systems-level understanding …
genomics which has opened the opportunity for gaining global, systems-level understanding …
Contribution of the PhoP-PhoQ and PmrA-PmrB Two-Component Regulatory Systems to Mg2+-Induced Gene Regulation in Pseudomonas aeruginosa
When grown in divalent cation-limited medium, Pseudomonas aeruginosa becomes
resistant to cationic antimicrobial peptides and polymyxin B. This resistance is regulated by …
resistant to cationic antimicrobial peptides and polymyxin B. This resistance is regulated by …
CARMAweb: comprehensive R-and bioconductor-based web service for microarray data analysis
Abstract CARMAweb (Comprehensive R-based Microarray Analysis web service) is a web
application designed for the analysis of microarray data. CARMAweb performs data …
application designed for the analysis of microarray data. CARMAweb performs data …
A TonB-dependent receptor constitutes the outer membrane transport system for a lignin-derived aromatic compound
TonB-dependent receptors (TBDRs) mediate substrate-specific transport across the outer
membrane, utilizing energy derived from the proton motive force transmitted from the TonB …
membrane, utilizing energy derived from the proton motive force transmitted from the TonB …
Histone H2A. Z is essential for estrogen receptor signaling
Incorporation of H2A. Z into the chromatin of inactive promoters has been shown to poise
genes for their expression. Here we provide strong evidence that H2A. Z is incorporated into …
genes for their expression. Here we provide strong evidence that H2A. Z is incorporated into …
Computational systems biology approaches for Parkinson's disease
E Glaab - Cell and tissue research, 2018 - Springer
Parkinson's disease (PD) is a prime example of a complex and heterogeneous disorder,
characterized by multifaceted and varied motor-and non-motor symptoms and different …
characterized by multifaceted and varied motor-and non-motor symptoms and different …