Whole-genome duplication (WGD) events have shaped the history of many evolutionary
lineages. One such duplication has been implicated in the evolution of teleost fishes, by far …

Protein evolution or engineering studies are traditionally focused on amino acid
substitutions and the way these contribute to fitness. Meanwhile, the insertion and deletion …

New genome assemblies have been arriving at a rapidly increasing pace, thanks to
decreases in sequencing costs and improvements in third-generation sequencing …

Exome sequencing studies of autism spectrum disorders (ASDs) have identified many de
novo mutations but few recurrently disrupted genes. We therefore developed a modified …

Comparative genomic analyses of primates offer considerable potential to define and
understand the processes that mold, shape, and transform the human genome. However …

Background Camellia is an economically and phylogenetically important genus in the family
Theaceae. Owing to numerous hybridization and polyploidization, it is taxonomically and …

The malaria parasite Plasmodium falciparum has a great capacity for evolutionary
adaptation to evade host immunity and develop drug resistance. Current understanding of …

Bacterial genomes vary extensively in terms of both gene content and gene sequence. This
plasticity hampers the use of traditional SNP-based methods for identifying all genetic …

All genetic variation arises via new mutations; therefore, determining the rate and biases for
different classes of mutation is essential for understanding the genetics of human disease …

Evolution is the fundamental physical process that gives rise to biological phenomena. Yet it
is widely treated as a subset of population genetics, and thus its scope is artificially limited …