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The epidemiology of prostate cancer
Prostate cancer is a major cause of disease and mortality among men, and each year 1.6
million men are diagnosed with and 366,000 men die of prostate cancer. In this review, we …
million men are diagnosed with and 366,000 men die of prostate cancer. In this review, we …
Metastasis: from dissemination to organ-specific colonization
Metastasis to distant organs is an ominous feature of most malignant tumours but the natural
history of this process varies in different cancers. The cellular origin, intrinsic properties of …
history of this process varies in different cancers. The cellular origin, intrinsic properties of …
Prostate-specific antigen screening and 15-year prostate cancer mortality: a secondary analysis of the CAP randomized clinical trial
Importance The Cluster Randomized Trial of PSA Testing for Prostate Cancer (CAP)
reported no effect of prostate-specific antigen (PSA) screening on prostate cancer mortality …
reported no effect of prostate-specific antigen (PSA) screening on prostate cancer mortality …
Metabolic Imaging of Patients with Prostate Cancer Using Hyperpolarized [1-13C]Pyruvate
This first-in-man imaging study evaluated the safety and feasibility of hyperpolarized [1-13C]
pyruvate as an agent for noninvasively characterizing alterations in tumor metabolism for …
pyruvate as an agent for noninvasively characterizing alterations in tumor metabolism for …
Prostate-cancer mortality at 11 years of follow-up
Background Several trials evaluating the effect of prostate-specific antigen (PSA) testing on
prostate-cancer mortality have shown conflicting results. We updated prostate-cancer …
prostate-cancer mortality have shown conflicting results. We updated prostate-cancer …
Predicting 15-year prostate cancer specific mortality after radical prostatectomy
Purpose: Long-term prostate cancer specific mortality after radical prostatectomy is poorly
defined in the era of widespread screening. An understanding of the treated natural history …
defined in the era of widespread screening. An understanding of the treated natural history …
Clinical results of long-term follow-up of a large, active surveillance cohort with localized prostate cancer
Purpose We assessed the outcome of a watchful-waiting protocol with selective delayed
intervention by using clinical prostate-specific antigen (PSA), or histologic progression as …
intervention by using clinical prostate-specific antigen (PSA), or histologic progression as …
Guideline for the management of clinically localized prostate cancer: 2007 update
I Thompson, JB Thrasher, G Aus, AL Burnett… - The Journal of …, 2007 - auajournals.org
In December 1995, the AUA published the Report on the Management of Clinically
Localized Prostate Cancer. 1 The document was the culmination of six years of work by 17 …
Localized Prostate Cancer. 1 The document was the culmination of six years of work by 17 …
20-year outcomes following conservative management of clinically localized prostate cancer
ContextThe appropriate therapy for men with clinically localized prostate cancer is uncertain.
A recent study suggested an increasing prostate cancer mortality rate for men who are alive …
A recent study suggested an increasing prostate cancer mortality rate for men who are alive …
SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression
Effective clinical management of prostate cancer (PCA) has been challenged by significant
intratumoural heterogeneity on the genomic and pathological levels and limited …
intratumoural heterogeneity on the genomic and pathological levels and limited …