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Sarcopenia in the older adult with cancer
The term sarcopenia, derived from the Greek words sarx for flesh and penia for loss, was first
introduced by Rosenberg 1 in 1989 to describe the loss of muscle mass that accompanies …
introduced by Rosenberg 1 in 1989 to describe the loss of muscle mass that accompanies …
[HTML][HTML] Forcing the vicious circle: sarcopenia increases toxicity, decreases response to chemotherapy and worsens with chemotherapy
F Bozzetti - Annals of oncology, 2017 - Elsevier
Sarcopenia has recently emerged as a new condition that, independently from malnutrition,
may adversely affect the prognosis of cancer patients. Purpose of this narrative review is to …
may adversely affect the prognosis of cancer patients. Purpose of this narrative review is to …
Tumor-derived IL-6 and trans-signaling among tumor, fat, and muscle mediate pancreatic cancer cachexia
JE Rupert, A Narasimhan, DHA Jengelley… - Journal of Experimental …, 2021 - rupress.org
Most patients with pancreatic adenocarcinoma (PDAC) suffer cachexia; some do not. To
model heterogeneity, we used patient-derived orthotopic xenografts. These phenocopied …
model heterogeneity, we used patient-derived orthotopic xenografts. These phenocopied …
Effects of weight loss and sarcopenia on response to chemotherapy, quality of life, and survival
It has frequently been shown that patients with cancer are one of the largest hospital patient
groups with a prevalence for malnutrition. Weight loss is a frequent manifestation of …
groups with a prevalence for malnutrition. Weight loss is a frequent manifestation of …
Diffuse large B-cell lymphoma: R-CHOP failure—what to do?
B Coiffier, C Sarkozy - Hematology 2014, the American Society …, 2016 - ashpublications.org
Although rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone (R-
CHOP) is the standard treatment for patients with diffuse large B-cell lymphoma (DLBCL),∼ …
CHOP) is the standard treatment for patients with diffuse large B-cell lymphoma (DLBCL),∼ …
Computed tomography-defined muscle and fat wasting are associated with cancer clinical outcomes
SMR Kazemi-Bajestani, VC Mazurak… - Seminars in cell & …, 2016 - Elsevier
Cancer cachexia (ie, skeletal muscle wasting with or without fat loss) relates to several
adverse outcomes. Computed tomography (CT) cross-sectional images serve as an efficient …
adverse outcomes. Computed tomography (CT) cross-sectional images serve as an efficient …
Prevalence and prognostic impact of cachexia among older patients with cancer: a nationwide cross‐sectional survey (NutriAgeCancer)
J Poisson, C Martinez‐Tapia, D Heitz… - Journal of cachexia …, 2021 - Wiley Online Library
Background Nutritional impairment is common in cancer patients and is associated with
poor outcomes. Only few studies focused on cachexia. We assessed the prevalence of …
poor outcomes. Only few studies focused on cachexia. We assessed the prevalence of …
The prevalence and prognostic value of low muscle mass in cancer patients: a review of the literature
HN Rier, A Jager, S Sleijfer, AB Maier… - The oncologist, 2016 - academic.oup.com
In several diseases, low muscle mass has been revealed as an unfavorable prognostic
factor for outcome. Whether this holds true in patients with solid malignancies as well has …
factor for outcome. Whether this holds true in patients with solid malignancies as well has …
[HTML][HTML] Cachexia and sarcopenia in older adults with cancer: a comprehensive review
Cancer cachexia is a syndrome characterized by weight loss with accompanying loss of
muscle and/or fat mass and leads to impaired patient function and physical performance and …
muscle and/or fat mass and leads to impaired patient function and physical performance and …
Body composition and sarcopenia: the next-generation of personalized oncology and pharmacology?
M Hilmi, A Jouinot, R Burns, F Pigneur… - Pharmacology & …, 2019 - Elsevier
Body composition has gained increasing attention in oncology in recent years due to fact
that sarcopenia has been revealed to be a strong prognostic indicator for survival across …
that sarcopenia has been revealed to be a strong prognostic indicator for survival across …