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Animal models for COVID-19
C Muñoz-Fontela, WE Dowling, SGP Funnell, PS Gsell… - Nature, 2020 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the aetiological agent of
coronavirus disease 2019 (COVID-19), an emerging respiratory infection caused by the …
coronavirus disease 2019 (COVID-19), an emerging respiratory infection caused by the …
Measuring immunity to SARS-CoV-2 infection: comparing assays and animal models
DS Khoury, AK Wheatley, MD Ramuta… - Nature Reviews …, 2020 - nature.com
The rapid scale-up of research on coronavirus disease 2019 (COVID-19) has spawned a
large number of potential vaccines and immunotherapies, accompanied by a …
large number of potential vaccines and immunotherapies, accompanied by a …
Defining the Syrian hamster as a highly susceptible preclinical model for SARS-CoV-2 infection
K Rosenke, K Meade-White, M Letko… - Emerging microbes & …, 2020 - Taylor & Francis
Following emergence in late 2019, SARS-CoV-2 rapidly became pandemic and is presently
responsible for millions of infections and hundreds of thousands of deaths worldwide. There …
responsible for millions of infections and hundreds of thousands of deaths worldwide. There …
SARS-CoV-2 infection of African green monkeys results in mild respiratory disease discernible by PET/CT imaging and shedding of infectious virus from both …
AL Hartman, S Nambulli, CM McMillen, AG White… - PLoS …, 2020 - journals.plos.org
Vaccines are urgently needed to combat the global coronavirus disease 2019 (COVID-19)
pandemic, and testing of candidate vaccines in an appropriate non-human primate (NHP) …
pandemic, and testing of candidate vaccines in an appropriate non-human primate (NHP) …
Genomic variation, origin tracing, and vaccine development of SARS-CoV-2: A systematic review
COVID-19 has spread globally to over 200 countries with more than 40 million confirmed
cases and one million deaths as of November 1, 2020. The SARS-CoV-2 virus, leading to …
cases and one million deaths as of November 1, 2020. The SARS-CoV-2 virus, leading to …
Development of a coronavirus disease 2019 nonhuman primate model using airborne exposure
SC Johnston, KM Ricks, A Jay, JL Raymond, F Rossi… - PloS one, 2021 - journals.plos.org
Airborne transmission is predicted to be a prevalent route of human exposure with SARS-
CoV-2. Aside from African green monkeys, nonhuman primate models that replicate …
CoV-2. Aside from African green monkeys, nonhuman primate models that replicate …
Nonhuman primates in translational research
AF Tarantal, SC Noctor… - Annual review of …, 2022 - annualreviews.org
Nonhuman primates are critically important animal models in which to study complex human
diseases, understand biological functions, and address the safety of new diagnostics and …
diseases, understand biological functions, and address the safety of new diagnostics and …
Cell and animal models of SARS-CoV-2 pathogenesis and immunity
The spread of the novel virus SARS coronavirus 2 (SARS-CoV-2) was explosive, with cases
first identified in December 2019, and> 22 million people infected and> 775,000 deaths as …
first identified in December 2019, and> 22 million people infected and> 775,000 deaths as …
Poxvirus MVA expressing SARS-CoV-2 S protein induces robust immunity and protects rhesus macaques from SARS-CoV-2
P Mooij, J García-Arriaza, P Pérez… - Frontiers in …, 2022 - frontiersin.org
Novel safe, immunogenic, and effective vaccines are needed to control the COVID-19
pandemic, caused by SARS-CoV-2. Here, we describe the safety, robust immunogenicity …
pandemic, caused by SARS-CoV-2. Here, we describe the safety, robust immunogenicity …
Evidence of a wide gap between COVID-19 in humans and animal models: a systematic review
SN Ehaideb, ML Abdullah, B Abuyassin, A Bouchama - Critical Care, 2020 - Springer
Background Animal models of COVID-19 have been rapidly reported after the start of the
pandemic. We aimed to assess whether the newly created models reproduce the full …
pandemic. We aimed to assess whether the newly created models reproduce the full …