G-quadruplex DNA for construction of biosensors

H Yang, Y Zhou, J Liu - TrAC Trends in Analytical Chemistry, 2020‏ - Elsevier
DNA-based biosensors have been widely used for its stable chemical properties, cost-
effectiveness, and easy modification. G-quadruplex (G4) DNA has attracted growing interest …

Thioflavin T as a fluorescence probe for biosensing applications

FY Khusbu, X Zhou, H Chen, C Ma, K Wang - TrAC Trends in Analytical …, 2018‏ - Elsevier
Thioflavin T (ThT), a water-soluble fluorescence probe and the conventional dye for the
detection of amyloid fibrils has recently been demonstrated to recognize and bind nucleic …

Recent advances on G-quadruplex for biosensing, bioimaging and cancer therapy

J Xu, R Jiang, H He, C Ma, Z Tang - TrAC Trends in Analytical Chemistry, 2021‏ - Elsevier
G-quadruplex is a three-dimensional secondary structure of nucleic acids formed by the
Hoogsteen hydrogen pairing of four guanines. Diverse topologies of G-quadruplex could be …

Dimeric G-quadruplex: an effective nucleic acid scaffold for lighting up thioflavin T

S **g, Q Liu, Y **, B Li - Analytical Chemistry, 2020‏ - ACS Publications
As a recently identified higher-order quadruplex (G4) structure, the G4 dimer possesses
unique structure and biological functions. In this work, we found accidentally that two tandem …

Rapid detection of multiple respiratory viruses based on microfluidic isothermal amplification and a real-time colorimetric method

R Wang, R Zhao, Y Li, W Kong, X Guo, Y Yang, F Wu… - Lab on a Chip, 2018‏ - pubs.rsc.org
Respiratory viruses are major threats causing development of acute respiratory tract
infections, which are common causes of illness and death throughout the world. Here, an …

DNA-mediated chemiluminescence bioassays

S Li, Y Jiang, R Huang, X Zhang - TrAC Trends in Analytical Chemistry, 2024‏ - Elsevier
In recent years, increasing attention has been paid to DNA mediated chemiluminescence
(CL) bioassays due to the merits provided by both of CL and functional DNAs. CL exhibits …

New G-triplex DNA dramatically activates the fluorescence of thioflavin T and acts as a turn-on fluorescent sensor for uracil-DNA glycosylase activity detection

LL Zhao, YX Gu, JH Dong, XT Li, HY Pan… - Analytical …, 2024‏ - ACS Publications
G-triplexes are G-rich oligonucleotides composed of three G-tracts and have absorbed much
attention due to their potential biological functions and attractive performance in biosensing …

Label-free and enzyme-free detection of microRNA based on a hybridization chain reaction with hemin/G-quadruplex enzymatic catalysis-induced MoS 2 quantum …

J Ge, Z Qi, L Zhang, X Shen, Y Shen, W Wang, Z Li - Nanoscale, 2020‏ - pubs.rsc.org
A new simple, sensitive and specific strategy for microRNA analysis has been described
based on a hybridization chain reaction with hemin/G-quadruplex enzymatic catalysis …

[HTML][HTML] Label-free G-quadruplex aptamer fluorescence assay for Ochratoxin A using a thioflavin T probe

K Wu, C Ma, H Zhao, H He, H Chen - Toxins, 2018‏ - mdpi.com
Ochratoxin A (OTA) is one of the most common mycotoxins contaminating feed and
foodstuffs. Therefore, a great deal of concern is associated with AFB1 toxicity. In this work, a …

Hairpin probe-based one-pot multiplex isothermal amplification combined with bifunctional G-quadruplex (IHP-GT) for the detection of alkaline phosphatase

S Zhu, S Zhou, L Deng, T Gu, J Li, J Chen, X Wang… - Analytica Chimica …, 2024‏ - Elsevier
Abnormal alkaline phosphatase (ALP) levels have been linked to breast cancer, prostate
cancer, bone damage, gingivitis and abnormal liver function. Monitoring ALP levels is …