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Soft lithography in biology and biochemistry
GM Whitesides, E Ostuni, S Takayama… - Annual review of …, 2001 - annualreviews.org
▪ Abstract Soft lithography, a set of techniques for microfabrication, is based on printing and
molding using elastomeric stamps with the patterns of interest in bas-relief. As a technique …
molding using elastomeric stamps with the patterns of interest in bas-relief. As a technique …
Genetic map** in human disease
Genetic map** provides a powerful approach to identify genes and biological processes
underlying any trait influenced by inheritance, including human diseases. We discuss the …
underlying any trait influenced by inheritance, including human diseases. We discuss the …
Initial sequencing and analysis of the human genome
US DOE Joint Genome Institute: Hawkins Trevor 4 … - nature, 2001 - nature.com
The human genome holds an extraordinary trove of information about human development,
physiology, medicine and evolution. Here we report the results of an international …
physiology, medicine and evolution. Here we report the results of an international …
The human genome browser at UCSC
As vertebrate genome sequences near completion and research refocuses to their analysis,
the issue of effective genome annotation display becomes critical. A mature web tool for …
the issue of effective genome annotation display becomes critical. A mature web tool for …
[HTML][HTML] Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior
T Sakurai, A Amemiya, M Ishii, I Matsuzaki… - Cell, 1998 - cell.com
The hypothalamus plays a central role in the integrated control of feeding and energy
homeostasis. We have identified two novel neuropeptides, both derived from the same …
homeostasis. We have identified two novel neuropeptides, both derived from the same …
Finishing the euchromatic sequence of the human genome
International Human Genome Sequencing Consortium - Nature, 2004 - nature.com
The sequence of the human genome encodes the genetic instructions for human
physiology, as well as rich information about human evolution. In 2001, the International …
physiology, as well as rich information about human evolution. In 2001, the International …
PTEN, a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer
J Li, C Yen, D Liaw, K Podsypanina, S Bose, SI Wang… - science, 1997 - science.org
Map** of homozygous deletions on human chromosome 10q23 has led to the isolation of
a candidate tumor suppressor gene, PTEN, that appears to be mutated at considerable …
a candidate tumor suppressor gene, PTEN, that appears to be mutated at considerable …
A novel MHC class I–like gene is mutated in patients with hereditary haemochromatosis
Hereditary haemochromatosis (HH), which affects some 1 in 400 and has an estimated
carrier frequency of 1 in 10 individuals of Northern European descent, results in multi–organ …
carrier frequency of 1 in 10 individuals of Northern European descent, results in multi–organ …
Large-scale identification, map**, and genoty** of single-nucleotide polymorphisms in the human genome
DG Wang, JB Fan, CJ Siao, A Berno, P Young… - Science, 1998 - science.org
Single-nucleotide polymorphisms (SNPs) are the most frequent type of variation in the
human genome, and they provide powerful tools for a variety of medical genetic studies. In a …
human genome, and they provide powerful tools for a variety of medical genetic studies. In a …
A deletion in the bovine myostatin gene causes the double–muscled phenotype in cattle
An exceptional muscle development commonly referred to as 'double-muscled'(Fig. 1) has
been seen in several cattle breeds and has attracted considerable attention from beef …
been seen in several cattle breeds and has attracted considerable attention from beef …