[HTML][HTML] Diet-gut microbiota-epigenetics in metabolic diseases: From mechanisms to therapeutics

D Li, Y Li, S Yang, J Lu, X **, M Wu - Biomedicine & Pharmacotherapy, 2022 - Elsevier
The prevalence of metabolic diseases, including obesity, dyslipidemia, type 2 diabetes
mellitus (T2DM), and non-alcoholic fatty liver disease (NAFLD), is a severe burden in human …

[HTML][HTML] Gut-muscle axis and sepsis-induced myopathy: The potential role of gut microbiota

Y Liu, L Xu, Z Yang, D Wang, T Li, F Yang, Z Li… - Biomedicine & …, 2023 - Elsevier
Sepsis is described as an immune response disorder of the host to infection in which
microorganisms play a non-negligible role. Most survivors of sepsis experience ICU …

Metabolites as risk factors for diabetic retinopathy in patients with type 2 diabetes: a 12-year follow-up study

L Fernandes Silva, J Hokkanen… - The Journal of …, 2024 - academic.oup.com
Context Diabetic retinopathy (DR) is a specific microvascular complication in patients with
diabetes and the leading cause of blindness. Recent advances in omics, especially …

Towards a Rosetta stone for metabolomics: recommendations to overcome inconsistent metabolite nomenclature

V Koistinen, O Kärkkäinen, P Keski-Rahkonen… - Nature …, 2023 - nature.com
The metabolomics literature suffers from ambiguity in the nomenclature for individual
metabolites, which introduces a disconnect between publications and leads to …

The paradigm change from reactive medical services to 3PM in ischemic stroke: a holistic approach utilising tear fluid multi-omics, mitochondria as a vital biosensor …

O Golubnitschaja, J Polivka Jr, P Potuznik, M Pesta… - EPMA Journal, 2024 - Springer
Worldwide stroke is the second leading cause of death and the third leading cause of death
and disability combined. The estimated global economic burden by stroke is over US $891 …

Gut microbial metabolic signatures in diabetes mellitus and potential preventive and therapeutic applications

E Garcia-Gutierrez, AK O'Mahony, RS Dos Santos… - Gut …, 2024 - Taylor & Francis
Diabetes mellitus can be subdivided into several categories based on origin and clinical
characteristics. The most common forms of diabetes are type 1 (T1D), type 2 diabetes (T2D) …

SIRT3 modulates endothelial mitochondrial redox state during insulin resistance

E Martino, A Balestrieri, C Anastasio, M Maione, L Mele… - Antioxidants, 2022 - mdpi.com
Emerging evidence indicates that defects in sirtuin signaling contribute to impaired glucose
and lipid metabolism, resulting in insulin resistance (IR) and endothelial dysfunction. Here …

Interactions between diet and gut microbiota in cancer

G Nakatsu, N Andreeva, MH MacDonald… - Nature Microbiology, 2024 - nature.com
Dietary patterns and specific dietary components, in concert with the gut microbiota, can
jointly shape susceptibility, resistance and therapeutic response to cancer. Which diet …

Role of the gut microbiome in skeletal muscle physiology and pathophysiology

C Lefevre, LB Bindels - Current osteoporosis reports, 2022 - Springer
Abstract Purpose of Review This review aims to summarize the recent findings about the
contribution of the gut microbiome to muscle pathophysiology and discuss molecular …

[HTML][HTML] Amino acid derivative of probenecid potentiates apoptosis-inducing effects of vinblastine by increasing oxidative stress in a cancer cell-specific manner

J Huttunen, J Tampio, J Järvinen, AB Montaser… - Chemico-Biological …, 2024 - Elsevier
Many chemotherapeutic drugs suffer from multidrug resistance (MDR). Efflux transporters,
namely ATP-binding cassettes (ABCs), that pump the drugs out of the cancer cells comprise …