[HTML][HTML] Screening strategies for quorum sensing inhibitors in combating bacterial infections
L Lu, M Li, G Yi, L Liao, Q Cheng, J Zhu… - Journal of …, 2022 - Elsevier
Interference with quorum sensing (QS) represents an antivirulence strategy with significant
promise for the treatment of bacterial infections and a new approach for restoring antibiotic …
promise for the treatment of bacterial infections and a new approach for restoring antibiotic …
An overview of biological and computational methods for designing mechanism-informed anti-biofilm agents
Bacterial biofilms are complex and highly antibiotic-resistant aggregates of microbes that
form on surfaces in the environment and body including medical devices. They are key …
form on surfaces in the environment and body including medical devices. They are key …
Folate-targeted curcumin-loaded niosomes for site-specific delivery in breast cancer treatment: In silico and In vitro study
B Honarvari, S Karimifard, N Akhtari, M Mehrarya… - Molecules, 2022 - mdpi.com
As the most common cancer in women, efforts have been made to develop novel
nanomedicine-based therapeutics for breast cancer. In the present study, the in silico …
nanomedicine-based therapeutics for breast cancer. In the present study, the in silico …
Combination of QSAR, molecular docking, molecular dynamic simulation and MM-PBSA: analogues of lopinavir and favipiravir as potential drug candidates against …
Pandemic COVID-19 infections have spread throughout the world. There is no effective
treatment against this disease. Viral RNA-dependent RNA polymerase (RdRp) catalyzes the …
treatment against this disease. Viral RNA-dependent RNA polymerase (RdRp) catalyzes the …
Para-chloro-meta-xylenol reshaped the fates of antibiotic resistance genes during sludge fermentation: Insights of cell membrane permeability, bacterial structure and …
W Du, T Wang, F Wang, Z Li, W Huang, J Tai… - Science of The Total …, 2022 - Elsevier
The occurrence of para-chloro-meta-xylenol (PCMX, as largely consumed antimicrobial
chemicals) in waste activated sludge (WAS) would pose environmental risks for WAS …
chemicals) in waste activated sludge (WAS) would pose environmental risks for WAS …
High-Throughput Virtual Screening for a New Class of Antagonist Targeting LasR of Pseudomonas aeruginosa
A Vetrivel, S Natchimuthu, V Subramanian… - ACS …, 2021 - ACS Publications
Pseudomonas aeruginosa, an opportunistic human pathogen, causes fatal effects in
patients with cystic fibrosis and immunocompromised individuals and leads to around 1000 …
patients with cystic fibrosis and immunocompromised individuals and leads to around 1000 …
Naringenin Inhibition of the Pseudomonas aeruginosa Quorum Sensing Response Is Based on Its Time-Dependent Competition With N-(3-Oxo-dodecanoyl)-L …
Bacterial quorum sensing (QS) is a cell-to-cell communication system that governs the
expression of a large set of genes involved in bacterial–host interactions, including the …
expression of a large set of genes involved in bacterial–host interactions, including the …
In silico Selection and Experimental Validation of FDA-Approved Drugs as Anti-quorum Sensing Agents
M Mellini, E Di Muzio, F D'Angelo, V Baldelli… - Frontiers in …, 2019 - frontiersin.org
The emergence of antibiotic resistant bacterial pathogens is increasing at an unprecedented
pace, calling for the development of new therapeutic options. Small molecules interfering …
pace, calling for the development of new therapeutic options. Small molecules interfering …
[HTML][HTML] Inhibitive effect of eugenol and its nanoemulsion on quorum sensing–mediated virulence factors and biofilm formation by Pseudomonas aeruginosa
Z Lou, KS Letsididi, F Yu, Z Pei, H Wang… - Journal of food …, 2019 - Elsevier
The aim of the present study was to evaluate the quorum sensing (QS) inhibition potential of
eugenol and eugenol nanoemulsion against QS-dependent virulence factor production and …
eugenol and eugenol nanoemulsion against QS-dependent virulence factor production and …
Virtual Screening of FDA-Approved Drugs against LasR of Pseudomonas aeruginosa for Antibiofilm Potential
Pseudomonas aeruginosa is a Gram-negative pathogenic bacterium that is present
commonly in soil and water and is responsible for causing septic shock, pneumonia, urinary …
commonly in soil and water and is responsible for causing septic shock, pneumonia, urinary …