Mass spectrometry-based proteomics as an emerging tool in clinical laboratories

AG Birhanu - Clinical proteomics, 2023 - Springer
Mass spectrometry (MS)-based proteomics have been increasingly implemented in various
disciplines of laboratory medicine to identify and quantify biomolecules in a variety of …

Recent developments of useful MALDI matrices for the mass spectrometric characterization of lipids

J Leopold, Y Popkova, KM Engel, J Schiller - Biomolecules, 2018 - mdpi.com
Matrix-assisted laser desorption/ionization (MALDI) is one of the most successful “soft”
ionization methods in the field of mass spectrometry and enables the analysis of a broad …

MALDI HiPLEX-IHC: multiomic and multimodal imaging of targeted intact proteins in tissues

MJ Lim, G Yagnik, C Henkel, SF Frost, T Bien… - Frontiers in …, 2023 - frontiersin.org
Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) is one
of the most widely used methods for imaging the spatial distribution of unlabeled small …

Recent developments of novel matrices and on-tissue chemical derivatization reagents for MALDI-MSI

Q Zhou, A Fülöp, C Hopf - Analytical and bioanalytical chemistry, 2021 - Springer
Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) is a fast-
growing technique for visualization of the spatial distribution of the small molecular and …

Empowering clinical diagnostics with mass spectrometry

S Banerjee - ACS omega, 2020 - ACS Publications
The unmet need for highly accurate methods of disease diagnosis poses new challenges for
developments in laboratory medicine. Advances in mass spectrometry (MS)-based disease …

Mass spectrometry imaging to detect lipid biomarkers and disease signatures in cancer

M Holzlechner, E Eugenin, B Prideaux - Cancer reports, 2019 - Wiley Online Library
Background Current methods to identify, classify, and predict tumor behavior mostly rely on
histology, immunohistochemistry, and molecular determinants. However, better predictive …

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: an update for 2019–2020

DJ Harvey - Mass Spectrometry Reviews, 2023 - Wiley Online Library
This review is the tenth update of the original article published in 1999 on the application of
matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry to the analysis of …

Mass spectrometry imaging technology in metabolomics: a systematic review

SQ Gao, JH Zhao, Y Guan, YS Tang… - Biomedical …, 2023 - Wiley Online Library
Mass spectrometry imaging (MSI) is a powerful label‐free analysis technique that can
provide simultaneous spatial distribution of multiple compounds in a single experiment. By …

Evolution of the liver biopsy and its future

D Jain, R Torres, R Celli, J Koelmel… - Translational …, 2021 - pmc.ncbi.nlm.nih.gov
Liver biopsies are commonly used to evaluate a wide variety of medical disorders, including
neoplasms and post-transplant complications. However, its use is being impacted by …

Mass spectrometry technologies to advance care for cancer patients in clinical and intraoperative use

J Zhang, M Sans, KY Garza… - Mass spectrometry …, 2021 - Wiley Online Library
Developments in mass spectrometry technologies have driven a widespread interest and
expanded their use in cancer‐related research and clinical applications. In this review, we …