Roles and mechanisms of exosomal non-coding RNAs in human health and diseases

C Li, YQ Ni, H Xu, QY **ang, Y Zhao, JK Zhan… - Signal transduction and …, 2021 - nature.com
Exosomes play a role as mediators of cell-to-cell communication, thus exhibiting pleiotropic
activities to homeostasis regulation. Exosomal non-coding RNAs (ncRNAs), mainly …

The implications of exosomes in pregnancy: emerging as new diagnostic markers and therapeutics targets

M Ghafourian, R Mahdavi, Z Akbari Jonoush… - Cell Communication and …, 2022 - Springer
Extracellular vehicles (EVs) are a heterogeneous group of cell and membranous particles
originating from different cell compartments. EVs participate in many essential physiological …

Advances in pathogenesis and treatment of essential hypertension

J Ma, X Chen - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
Hypertension is a significant risk factor for cardiovascular and cerebrovascular diseases and
the leading cause of premature death worldwide. However, the pathogenesis of the …

Inverse salt sensitivity of blood pressure: mechanisms and potential relevance for prevention of cardiovascular disease

RA Felder, JJ Gildea, P Xu, W Yue, I Armando… - Current hypertension …, 2022 - Springer
Abstract Purpose of Review To review the etiology of inverse salt sensitivity of blood
pressure (BP). Recent Findings Both high and low sodium (Na+) intake can be associated …

Extracellular vesicles as novel drug-delivery systems through intracellular communications

Y Matsuzaka, R Yashiro - Membranes, 2022 - mdpi.com
Since it has been reported that extracellular vesicles (EVs) carry cargo using cell-to-cell
comminication according to various in vivo situations, they are exprected to be applied as …

A Machine Learning Model Based on microRNAs for the Diagnosis of Essential Hypertension

A Jusic, I Junuzovic, A Hujdurovic, L Zhang, M Vausort… - Non-coding RNA, 2023 - mdpi.com
Introduction: Hypertension is a major and modifiable risk factor for cardiovascular diseases.
Essential, primary, or idiopathic hypertension accounts for 90–95% of all cases. Identifying …

Emerging role of exosomes in vascular diseases

Y Ren, H Zhang - Frontiers in Cardiovascular Medicine, 2023 - frontiersin.org
Exosomes are biological small spherical lipid bilayer vesicles secreted by most cells in the
body. Their contents include nucleic acids, proteins, and lipids. Exosomes can transfer …

Inverse salt sensitivity of blood pressure is associated with an increased renin-angiotensin system activity

JJ Gildea, P Xu, KA Schiermeyer, W Yue, RM Carey… - Biomedicines, 2022 - mdpi.com
High and low sodium diets are associated with increased blood pressure and
cardiovascular morbidity and mortality. The paradoxical response of elevated BP in low salt …

Current status of myocardial restoration via the paracrine function of mesenchymal stromal cells

M Nguyen-Truong, P Hematti… - American Journal of …, 2021 - journals.physiology.org
Mesenchymal stromal cells (MSCs) have been studied for nearly two decades as a therapy
for myocardial restoration. An emerging direction to repair myocardium is through their …

Chymase in plasma and urine extracellular vesicles: novel biomarkers for primary hypertension

S Ahmad, G Deep, HA Punzi, Y Su, S Singh, A Kumar… - medRxiv, 2023 - medrxiv.org
ABSTRACT BACKGROUND Extracellular vesicles (EVs) have emerged as a promising
liquid biopsy for various diseases. For the first time, using plasma and urinary EVs, we …