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Microbiome-based therapeutics
Symbiotic microorganisms inhabiting the gastrointestinal tract promote health by decreasing
susceptibility to infection and enhancing resistance to a range of diseases. In this Review …
susceptibility to infection and enhancing resistance to a range of diseases. In this Review …
Gut microbiota and immune system interactions
Dynamic interactions between gut microbiota and a host's innate and adaptive immune
systems are essential in maintaining intestinal homeostasis and inhibiting inflammation. Gut …
systems are essential in maintaining intestinal homeostasis and inhibiting inflammation. Gut …
Gut dysbiosis: Ecological causes and causative effects on human disease
The gut microbiota plays a role in many human diseases, but high-throughput sequence
analysis does not provide a straightforward path for defining healthy microbial communities …
analysis does not provide a straightforward path for defining healthy microbial communities …
Salmonella Typhimurium and inflammation: a pathogen-centric affair
JE Galán - Nature Reviews Microbiology, 2021 - nature.com
Microbial infections are controlled by host inflammatory responses that are initiated by
innate immune receptors after recognition of conserved microbial products. As inflammation …
innate immune receptors after recognition of conserved microbial products. As inflammation …
Host–microbiota interactions in inflammatory bowel disease
The mammalian intestine is colonized by trillions of microorganisms that have co-evolved
with the host in a symbiotic relationship. The presence of large numbers of symbionts near …
with the host in a symbiotic relationship. The presence of large numbers of symbionts near …
The role of Enterobacteriaceae in gut microbiota dysbiosis in inflammatory bowel diseases
Inflammatory bowel diseases (IBDs) are a group of chronic gastrointestinal inflammatory
diseases with unknown etiology. There is a combination of well documented factors in their …
diseases with unknown etiology. There is a combination of well documented factors in their …
[HTML][HTML] Mechanism of the gut microbiota colonization resistance and enteric pathogen infection
The mammalian gut microbial community, known as the gut microbiota, comprises trillions of
bacteria, which co-evolved with the host and has an important role in a variety of host …
bacteria, which co-evolved with the host and has an important role in a variety of host …
The microbiome, cancer, and cancer therapy
BA Helmink, MAW Khan, A Hermann… - Nature medicine, 2019 - nature.com
With the advent of next-generation sequencing, we have an unprecedented ability to study
tumor and host genomes as well as those of the vast array of microorganisms that exist …
tumor and host genomes as well as those of the vast array of microorganisms that exist …
Commensal consortia decolonize Enterobacteriaceae via ecological control
Persistent colonization and outgrowth of potentially pathogenic organisms in the intestine
can result from long-term antibiotic use or inflammatory conditions, and may perpetuate …
can result from long-term antibiotic use or inflammatory conditions, and may perpetuate …
The impact of oxidative stress in human pathology: Focus on gastrointestinal disorders
R Vona, L Pallotta, M Cappelletti, C Severi… - Antioxidants, 2021 - mdpi.com
Accumulating evidence shows that oxidative stress plays an essential role in the
pathogenesis and progression of many diseases. The imbalance between the production of …
pathogenesis and progression of many diseases. The imbalance between the production of …