A guide to artificial intelligence for cancer researchers

R Perez-Lopez, N Ghaffari Laleh, F Mahmood… - Nature Reviews …, 2024 - nature.com
Artificial intelligence (AI) has been commoditized. It has evolved from a specialty resource to
a readily accessible tool for cancer researchers. AI-based tools can boost research …

MRI segmentation of the human brain: challenges, methods, and applications

I Despotović, B Goossens… - … mathematical methods in …, 2015 - Wiley Online Library
Image segmentation is one of the most important tasks in medical image analysis and is
often the first and the most critical step in many clinical applications. In brain MRI analysis …

Locoregional delivery of IL-13Rα2-targeting CAR-T cells in recurrent high-grade glioma: a phase 1 trial

CE Brown, JC Hibbard, D Alizadeh, MS Blanchard… - Nature medicine, 2024 - nature.com
Chimeric antigen receptor T cell (CAR-T) therapy is an emerging strategy to improve
treatment outcomes for recurrent high-grade glioma, a cancer that responds poorly to current …

Large-scale pancreatic cancer detection via non-contrast CT and deep learning

K Cao, Y **a, J Yao, X Han, L Lambert, T Zhang… - Nature medicine, 2023 - nature.com
Pancreatic ductal adenocarcinoma (PDAC), the most deadly solid malignancy, is typically
detected late and at an inoperable stage. Early or incidental detection is associated with …

Amos: A large-scale abdominal multi-organ benchmark for versatile medical image segmentation

Y Ji, H Bai, C Ge, J Yang, Y Zhu… - Advances in neural …, 2022 - proceedings.neurips.cc
Despite the considerable progress in automatic abdominal multi-organ segmentation from
CT/MRI scans in recent years, a comprehensive evaluation of the models' capabilities is …

Multimodal integration of radiology, pathology and genomics for prediction of response to PD-(L) 1 blockade in patients with non-small cell lung cancer

RS Vanguri, J Luo, AT Aukerman, JV Egger, CJ Fong… - Nature cancer, 2022 - nature.com
Immunotherapy is used to treat almost all patients with advanced non-small cell lung cancer
(NSCLC); however, identifying robust predictive biomarkers remains challenging. Here we …

Genome-wide association meta-analysis identifies 17 loci associated with nonalcoholic fatty liver disease

Y Chen, X Du, A Kuppa, MF Feitosa, LF Bielak… - Nature …, 2023 - nature.com
Nonalcoholic fatty liver disease (NAFLD) is common and partially heritable and has no
effective treatments. We carried out a genome-wide association study (GWAS) meta …

Identification of direct connections between the dura and the brain

LCD Smyth, D Xu, SV Okar, T Dykstra, J Rustenhoven… - Nature, 2024 - nature.com
The arachnoid barrier delineates the border between the central nervous system and dura
mater. Although the arachnoid barrier creates a partition, communication between the …

A massive 7T fMRI dataset to bridge cognitive neuroscience and artificial intelligence

EJ Allen, G St-Yves, Y Wu, JL Breedlove… - Nature …, 2022 - nature.com
Extensive sampling of neural activity during rich cognitive phenomena is critical for robust
understanding of brain function. Here we present the Natural Scenes Dataset (NSD), in …

Federated learning enables big data for rare cancer boundary detection

S Pati, U Baid, B Edwards, M Sheller, SH Wang… - Nature …, 2022 - nature.com
Although machine learning (ML) has shown promise across disciplines, out-of-sample
generalizability is concerning. This is currently addressed by sharing multi-site data, but …