The great clinical success of cisplatin and its derivatives has convinced people that metal
complexes could play a more significant role in human cancer therapy. However, targeting …

While medicinal inorganic chemistry has been practised for over 5000 years, it was not until
the late 1800s when Alfred Werner published his ground-breaking research on coordination …

Organometallic reagents and metal catalysts are used ubiquitously in academia and
industry. Not surprisingly, the biological activity and environmental danger of metal …

Metal-based drugs and imaging agents are extensively used in the clinic for the treatment
and diagnosis of cancers and a wide range of other diseases. The current clinical arsenal of …

Immunogenic cell death (ICD) is a vital component of therapeutically induced anti‐tumor
immunity. An iridium (III) complex (Ir1), containing an N, N‐bis (2‐chloroethyl)‐azane …

Polyoxometalates (POMs) are an emerging class of inorganic metal oxides, which over the
last decades demonstrated promising biological activities by the virtue of their great diversity …

Ferrocene derivatives have attracted significant interest as anticancer, antibacterial,
antifungal and antiparasitic drug candidates. Discovered in the 1990s, the two most …

Anticancer metallodrugs based on ruthenium and osmium are among the most investigated
and advanced non-platinum metallodrugs. Inorganic drug discovery with these agents has …

Despite metal‐based photosensitizers showing great potential in photodynamic therapy for
tumor treatment, the application of the photosensitizers is intrinsically limited by their poor …

The immune system deploys a multitude of innate and adaptive mechanisms not only to
ward off pathogens but also to prevent malignant transformation (“immune surveillance”) …