Malaria in Brazil, Colombia, Peru and Venezuela: current challenges in malaria control and elimination

J Recht, AM Siqueira, WM Monteiro, SM Herrera… - Malaria journal, 2017 - Springer
In spite of significant progress towards malaria control and elimination achieved in South
America in the 2000s, this mosquito-transmitted tropical disease remains an important public …

malERA: an updated research agenda for malaria elimination and eradication

RN Rabinovich, C Drakeley, AA Djimde, BF Hall… - PLoS …, 2017 - journals.plos.org
Achieving a malaria-free world presents exciting scientific challenges as well as
overwhelming health, equity, and economic benefits. WHO and countries are setting …

Plasmodium falciparum is evolving to escape malaria rapid diagnostic tests in Ethiopia

SM Feleke, EN Reichert, H Mohammed… - Nature …, 2021 - nature.com
In Africa, most rapid diagnostic tests (RDTs) for falciparum malaria recognize histidine-rich
protein 2 antigen. Plasmodium falciparum parasites lacking histidine-rich protein 2 (pfhrp2) …

An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples

A Ahouidi, M Ali, J Almagro-Garcia… - Wellcome open …, 2021 - pmc.ncbi.nlm.nih.gov
MalariaGEN is a data-sharing network that enables groups around the world to work
together on the genomic epidemiology of malaria. Here we describe a new release of …

Major threat to malaria control programs by Plasmodium falciparum lacking histidine-rich protein 2, Eritrea

A Berhane, K Anderson, S Mihreteab… - Emerging infectious …, 2018 - pmc.ncbi.nlm.nih.gov
False-negative results for Plasmodium falciparum histidine-rich protein (HRP) 2–based
rapid diagnostic tests (RDTs) are increasing in Eritrea. We investigated HRP gene 2/3 …

High-throughput Plasmodium falciparum hrp2 and hrp3 gene deletion ty** by digital PCR to monitor malaria rapid diagnostic test efficacy

CA Vera-Arias, A Holzschuh, CO Oduma, K Badu… - Elife, 2022 - elifesciences.org
Most rapid diagnostic tests for Plasmodium falciparum malaria target the Histidine-Rich
Proteins 2 and 3 (HRP2 and HRP3). Deletions of the hrp2 and hrp3 genes result in false …

Plasmodium falciparum parasites lacking histidine-rich protein 2 and 3: a review and recommendations for accurate reporting

Q Cheng, ML Gatton, J Barnwell, P Chiodini… - Malaria journal, 2014 - Springer
Malaria rapid diagnostic tests (RDTs) play a critical role in malaria case management,
surveillance and case investigations. Test performance is largely determined by design and …

Pfhrp2-Deleted Plasmodium falciparum Parasites in the Democratic Republic of the Congo: A National Cross-sectional Survey

JB Parr, R Verity, SM Doctor, M Janko… - The Journal of …, 2017 - academic.oup.com
Abstract Background. Rapid diagnostic tests (RDTs) account for more than two-thirds of
malaria diagnoses in Africa. Deletions of the Plasmodium falciparum hrp2 (pfhrp2) gene …

Plasmodium falciparum histidine rich protein-2 diversity and the implications for PfHRP 2: based malaria rapid diagnostic tests in Ghana

LE Amoah, J Abankwa, A Oppong - Malaria journal, 2016 - Springer
Background Malaria rapid diagnostic tests (RDTs) play a key role in malaria management
and control. The PfHRP-2 based RDT is the most widely used RDT for malaria diagnosis in …

[HTML][HTML] Factors affecting the performance of HRP2-based malaria rapid diagnostic tests

X Martiáñez-Vendrell, M Skjefte, R Sikka… - Tropical Medicine and …, 2022 - mdpi.com
The recent COVID-19 pandemic has profoundly impacted global malaria elimination
programs, resulting in a sharp increase in malaria morbidity and mortality. To reduce this …