Therapeutic prospects of naturally occurring p38 MAPK inhibitors tanshinone IIA and pinocembrin for the treatment of SARS‐CoV‐2‐induced CNS complications
M Valipour - Phytotherapy Research, 2023 - Wiley Online Library
P38 mitogen‐activated protein kinase (p38 MAPK) signaling pathway is closely related to
severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) replication and …
severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) replication and …
Saliva swabs are the preferred sample for Omicron detection
The Omicron variant is characterised by more than 50 distinct mutations, the majority of
which are located in the spike protein. The implications of these mutations for disease …
which are located in the spike protein. The implications of these mutations for disease …
Improved oral detection is a characteristic of Omicron infection and has implications for clinical sampling and tissue tropism
Abstract Background: The Omicron variant of concern is characterised by more than 50
distinct mutations, most in the spike protein. The implications of these for disease …
distinct mutations, most in the spike protein. The implications of these for disease …
Assessing the clinical severity of the Omicron variant in the Western Cape Province, South Africa, using the diagnostic PCR proxy marker of RdRp target delay to …
Background At present, it is unclear whether the extent of reduced risk of severe disease
seen with SARS-Cov-2 Omicron variant infection is caused by a decrease in variant …
seen with SARS-Cov-2 Omicron variant infection is caused by a decrease in variant …
[HTML][HTML] Omicron and Delta variant prevalence detection and identification during the fourth COVID-19 wave in Mexico using wastewater-based epidemiology
A Aguayo-Acosta, MA Oyervides-Muñoz… - IJID regions, 2024 - Elsevier
Objectives To identify the SARS-CoV-2 variants Delta and Omicron during the fourth wave of
the COVID-19 pandemic in Mexico using samples taken from 19 locations in 18 out of the 32 …
the COVID-19 pandemic in Mexico using samples taken from 19 locations in 18 out of the 32 …
A comparative analysis exposes an amplification delay distinctive to SARS-CoV-2 Omicron variants of clinical and public health relevance
KL Brown, A Ceci, C Roby, R Briggs… - Emerging Microbes & …, 2023 - Taylor & Francis
Mutations in the SARS-CoV-2 genome may negatively impact a diagnostic test, have no
effect, or turn into an opportunity for rapid molecular screening of variants. Using an in …
effect, or turn into an opportunity for rapid molecular screening of variants. Using an in …
How South Africa used national cycle threshold (ct) values to continuously monitor SARS-CoV-2 laboratory test quality
The high demand for SARS-CoV-2 tests but limited supply to South African laboratories
early in the COVID-19 pandemic resulted in a heterogenous diagnostic footprint of open and …
early in the COVID-19 pandemic resulted in a heterogenous diagnostic footprint of open and …
Monitoring SARS-CoV-2 variant transitions using differences in diagnostic cycle threshold values of target genes
AE Bordoy, V Saludes, D Panisello Yagüe, G Clarà… - Scientific Reports, 2022 - nature.com
Monitoring the emergence of new SARS-CoV-2 variants is important to detect potential risks
of increased transmission or disease severity. We investigated the identification of SARS …
of increased transmission or disease severity. We investigated the identification of SARS …
Higher mortality associated with the SARS-CoV-2 Delta variant in the Western Cape, South Africa, using RdRp target delay as a proxy
A novel proxy for the Delta variant, RNA-dependent RNA polymerase target delay in the
Seegene Allplex™ 2019-nCoV PCR assay, was associated with higher mortality (adjusted …
Seegene Allplex™ 2019-nCoV PCR assay, was associated with higher mortality (adjusted …
[HTML][HTML] Evaluation of SARS-CoV-2 diagnostics and risk factors associated with SARS-CoV-2 infection in Zambia
J Tembo, NF Egbe, K Maluzi, K Mulonga… - International Journal of …, 2022 - Elsevier
Objectives To conduct a diagnostic validation study of SARS-CoV-2 diagnostic kits. Methods
We compared SARS-CoV-2 diagnostic test results from 3 RT-PCR assays used by the …
We compared SARS-CoV-2 diagnostic test results from 3 RT-PCR assays used by the …