More than 10 years ago, we published the paper describing the mothur software package in
Applied and Environmental Microbiology. Our goal was to create a comprehensive package …

Phylogenetic surveys of soil ecosystems have shown that the number of prokaryotic species
found in a single sample exceeds that of known cultured prokaryotes. Soil metagenomics …

ABSTRACT mothur aims to be a comprehensive software package that allows users to use a
single piece of software to analyze community sequence data. It builds upon previous tools …

The human endogenous intestinal microflora is an essential “organ” in providing
nourishment, regulating epithelial development, and instructing innate immunity; yet …

We introduce here a new method for computing differences between microbial communities
based on phylogenetic information. This method, UniFrac, measures the phylogenetic …

Numerous studies are currently underway to characterize the microbial communities
inhabiting our world. These studies aim to dramatically expand our understanding of the …

Microbes are difficult to culture. Consequently, the primary source of information about a
fundamental evolutionary topic, life's diversity, is the environmental distribution of gene …

Although copious qualitative information describes the members of the diverse microbial
communities on Earth, statistical approaches for quantifying and comparing the numbers …

The microbiota of the human stomach and the influence of Helicobacter pylori colonization
on its composition remain largely unknown. We characterized bacterial diversity within the …

Background Moving beyond pairwise significance tests to compare many microbial
communities simultaneously is critical for understanding large-scale trends in microbial …