Glycoconjugates are major constituents of mammalian cells that are formed via covalent
conjugation of carbohydrates to other biomolecules like proteins and lipids and often …

Lipopolysaccharide (LPS) is the main structural component of the outer membrane of most
Gram-negative bacteria and has diverse immunostimulatory and procoagulant effects. Even …

Lipopolysaccharide (LPS) is a crucial constituent of the outer membrane of most Gram-
negative bacteria, playing a fundamental role in the protection of bacteria from …

Modern subunit vaccines based on homogeneous antigens offer more precise targeting and
improved safety compared with traditional whole-pathogen vaccines. However, they are also …

Interferon (IFN)-Is are crucial mediators of antiviral immunity and homeostatic immune
system regulation. However, the source of IFN-I signaling under homeostatic conditions is …

Following their initial discovery in the 1940s, polymyxin antibiotics fell into disfavor due to
their potential clinical toxicity, especially nephrotoxicity. However, the dry antibiotic …

Structural determination of carbohydrates is mostly performed by liquid-state NMR, and it is
a demanding task because the NMR signals of these biomolecules explore a rather narrow …

The antimicrobial resistance crisis is a global health issue requiring discovery and
development of novel therapeutics. However, conventional screening of natural products or …

Lipopolysaccharides (LPS) of Gram negative bacteria are one of the most potent stimulators
of the host innate immune system and LPS recognition is essential for the host organism to …

Lipid research represents a frontier for microbiology, as showcased by hopanoid lipids.
Hopanoids, which resemble sterols and are found in the membranes of diverse bacteria …