Cancer vaccines as promising immuno-therapeutics: platforms and current progress

J Liu, M Fu, M Wang, D Wan, Y Wei, X Wei - Journal of Hematology & …, 2022 - Springer
Research on tumor immunotherapy has made tremendous progress in the past decades,
with numerous studies entering the clinical evaluation. The cancer vaccine is considered a …

Hot and cold tumors: Immunological features and the therapeutic strategies

L Wang, H Geng, Y Liu, L Liu, Y Chen, F Wu, Z Liu… - MedComm, 2023 - Wiley Online Library
Abstract The “hotness” or “coldness” of the tumors are determined by the information of the
cancer cells themselves, tumor immune characteristics, tumor microenvironment, and …

Recent advances and challenges in cancer immunotherapy

C Peterson, N Denlinger, Y Yang - Cancers, 2022 - mdpi.com
Simple Summary Immunotherapy helps a person's immune system to target tumor cells.
Recent advances in cancer immunotherapy, including immune checkpoint inhibition …

Best Practices for Spatial Profiling for Breast Cancer Research with the GeoMx® Digital Spatial Profiler

H Bergholtz, JM Carter, A Cesano, MCU Cheang… - Cancers, 2021 - mdpi.com
Simple Summary In breast cancer, there is a high degree of variability in tumors and the
surrounding tissue called the tumor microenvironment (TME). To better understand tumor …

Clinical trials of self-replicating RNA-based cancer vaccines

MA Morse, EJ Crosby, J Force, T Osada… - Cancer Gene …, 2023 - nature.com
Therapeutic cancer vaccines, designed to activate immune effectors against tumor antigens,
utilize a number of different platforms for antigen delivery. Among these are messenger …

Advances in nanoparticle-based mRNA delivery for liver cancer and liver-associated infectious diseases

S Chung, CM Lee, M Zhang - Nanoscale horizons, 2023 - pubs.rsc.org
The liver is a vital organ that functions to detoxify the body. Liver cancer and infectious
diseases such as influenza and malaria can fatally compromise liver function. mRNA …

Vaccines in breast cancer: challenges and breakthroughs

GN Fatima, H Fatma, SK Saraf - Diagnostics, 2023 - mdpi.com
Breast cancer is a problem for women's health globally. Early detection techniques come in
a variety of forms ranging from local to systemic and from non-invasive to invasive. The …

mRNA vaccination in breast cancer: current progress and future direction

X Jiang, Q Liu - Journal of Cancer Research and Clinical Oncology, 2023 - Springer
Messenger RNA (mRNA) vaccination has proven to be highly successful in combating
Coronavirus disease 2019 (COVID-19) and has recently sparked tremendous interest. This …

Immunotherapies against HER2-positive breast cancer

S Duro-Sánchez, MR Alonso, J Arribas - Cancers, 2023 - mdpi.com
Simple Summary A wide range of treatments are available for HER2-positive breast cancer,
which have greatly improved the prognosis and quality of life of these patients. However …

Immunotherapy for HER-2 positive breast cancer

T Yang, L Kang, D Li, Y Song - Frontiers in Oncology, 2023 - frontiersin.org
Immunotherapy is a develo** treatment for advanced breast cancer. Immunotherapy has
clinical significance for the treatment of triple-negative breast cancers and human epidermal …