lncRNA biomarkers of glioblastoma multiforme

M Pokorná, M Černá, S Boussios, SV Ovsepian… - Biomedicines, 2024‏ - mdpi.com
Long noncoding RNAs (lncRNAs) are RNA molecules of 200 nucleotides or more in length
that are not translated into proteins. Their expression is tissue-specific, with the vast majority …

Evolving cell states and oncogenic drivers during the progression of IDH-mutant gliomas

J Wu, LN Gonzalez Castro, S Battaglia, CA El Farran… - Nature Cancer, 2024‏ - nature.com
Isocitrate dehydrogenase (IDH) mutants define a class of gliomas that are initially slow-
growing but inevitably progress to fatal disease. To characterize their malignant cell …

Glioblastoma stem cell long non-coding RNAs: therapeutic perspectives and opportunities

R Hazra, R Debnath, A Tuppad - Frontiers in Genetics, 2024‏ - frontiersin.org
Glioblastoma poses a formidable challenge among primary brain tumors: its tumorigenic
stem cells, capable of self-renewal, proliferation, and differentiation, contribute substantially …

Positive feedback loop of c-myc/XTP6/NDH2/NF-κB to promote malignant progression in glioblastoma

F ** integrative and retrospective cell atlas of gliomas
Z Xu, L Chen, X Lin, Y Lyu, M Zhou, H Chen, H Zhang… - bioRxiv, 2023‏ - biorxiv.org
Single-cell RNA sequencing (scRNA-seq) has dramatically transformed biomedical
research within laboratory settings. It has been extensively employed to investigate the …