Protein-protein interaction networks (PPI) and complex diseases

N Safari-Alighiarloo, M Taghizadeh… - … from bed to bench, 2014 - pmc.ncbi.nlm.nih.gov
The physical interaction of proteins which lead to compiling them into large densely
connected networks is a noticeable subject to investigation. Protein interaction networks are …

Systems biology approaches to understand the host–microbiome interactions in neurodegenerative diseases

D Rosario, J Boren, M Uhlen, G Proctor… - Frontiers in …, 2020 - frontiersin.org
Neurodegenerative diseases (NDDs) comprise a broad range of progressive neurological
disorders with multifactorial etiology contributing to disease pathophysiology. Evidence of …

[Књига][B] Random graphs and complex networks

R Van Der Hofstad - 2024 - books.google.com
" This rigorous introduction to network science presents random graphs as models for real-
world networks. Such networks have distinctive empirical properties and a wealth of new …

[HTML][HTML] Anhedonia and reward-circuit connectivity distinguish nonresponders from responders to dorsomedial prefrontal repetitive transcranial magnetic stimulation in …

J Downar, J Geraci, TV Salomons, K Dunlop… - Biological …, 2014 - Elsevier
Background Depression is a heterogeneous mental illness. Neurostimulation treatments, by
targeting specific nodes within the brain's emotion-regulation network, may be useful both as …

Systems approaches and polypharmacology for drug discovery from herbal medicines: an example using licorice

H Liu, J Wang, W Zhou, Y Wang, L Yang - Journal of ethnopharmacology, 2013 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: Licorice, one of the oldest and most popular
herbal medicines in the world, has been widely used in traditional Chinese medicine as a …

Graph analysis of epileptogenic networks in human partial epilepsy

C Wilke, G Worrell, B He - Epilepsia, 2011 - Wiley Online Library
Purpose: The current gold standard for the localization of the cortical regions responsible for
the initiation and propagation of the ictal activity is through the use of invasive …

[PDF][PDF] Random graphs and complex networks

R Van Der Hofstad - vol. I, 2014 - Citeseer
These lecture notes are intended to be used for master courses, where the students have a
limited prior knowledge of special topics in probability. Therefore, we have included many of …

Dissection of hubs and bottlenecks in a protein-protein interaction network

C Nithya, M Kiran, HA Nagarajaram - Computational Biology and …, 2023 - Elsevier
Abstract Analysis of degree centrality in conjunction with betweenness centrality of proteins
in a human protein-protein interaction network revealed three categories of centrally …

[HTML][HTML] Gene co-expression network analysis for identifying genetic markers in Parkinson's disease-a three-way comparative approach

G George, S Singh, SB Lokappa, J Varkey - Genomics, 2019 - Elsevier
Parkinson's disease (PD) is a neurodegenerative disorder involving progressive
deterioration of dopaminergic neurons. Although few genetic markers for familial PD are …

Genomic convergence and network analysis approach to identify candidate genes in Alzheimer's disease

P Talwar, Y Silla, S Grover, M Gupta, R Agarwal… - BMC genomics, 2014 - Springer
Background Alzheimer's disease (AD) is one of the leading genetically complex and
heterogeneous disorder that is influenced by both genetic and environmental factors. The …