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The mitophagy pathway and its implications in human diseases
S Wang, H Long, L Hou, B Feng, Z Ma, Y Wu… - Signal transduction and …, 2023 - nature.com
Mitochondria are dynamic organelles with multiple functions. They participate in necrotic cell
death and programmed apoptotic, and are crucial for cell metabolism and survival …
death and programmed apoptotic, and are crucial for cell metabolism and survival …
Autophagy-dependent ferroptosis in cancer
Significance: Autophagy is a self-degrading process that determines cell fate in response to
various environmental stresses. In contrast to autophagy-mediated cell survival, the signals …
various environmental stresses. In contrast to autophagy-mediated cell survival, the signals …
The beneficial role of autophagy in multiple sclerosis: yes or no?
HM Al-Kuraishy, MS Jabir, AI Al-Gareeb, HM Saad… - Autophagy, 2024 - Taylor & Francis
Multiple sclerosis (MS) is a chronic progressive demyelinating disease of the central
nervous system (CNS) due to an increase of abnormal peripherally auto-reactive T …
nervous system (CNS) due to an increase of abnormal peripherally auto-reactive T …
[HTML][HTML] Mitochondrial dysfunction route as a possible biomarker and therapy target for human cancer
R Al-Faze, HA Ahmed, MA El-Atawy, H Zagloul… - Biomedical Journal, 2024 - Elsevier
Mitochondria are vital organelles found within living cells and have signalling, biosynthetic,
and bioenergetic functions. Mitochondria play a crucial role in metabolic reprogramming …
and bioenergetic functions. Mitochondria play a crucial role in metabolic reprogramming …
New insights into the interplay between autophagy and oxidative and endoplasmic reticulum stress in neuronal cell death and survival
Y Gao, C Wang, D Jiang, G An, F **… - Frontiers in Cell and …, 2022 - frontiersin.org
Autophagy is a dynamic process that maintains the normal homeostasis of cells by digesting
and degrading aging proteins and damaged organelles. The effect of autophagy on neural …
and degrading aging proteins and damaged organelles. The effect of autophagy on neural …
Autophagopathies: from autophagy gene polymorphisms to precision medicine for human diseases
I Grosjean, B Roméo, MA Domdom, A Belaid… - Autophagy, 2022 - Taylor & Francis
At a time when complex diseases affect globally 280 million people and claim 14 million
lives every year, there is an urgent need to rapidly increase our knowledge into their …
lives every year, there is an urgent need to rapidly increase our knowledge into their …
Cocaine perturbs mitovesicle biology in the brain
P D'Acunzo, JM Ungania, Y Kim… - Journal of …, 2023 - Wiley Online Library
Cocaine, an addictive psychostimulant, has a broad mechanism of action, including the
induction of a wide range of alterations in brain metabolism and mitochondrial homeostasis …
induction of a wide range of alterations in brain metabolism and mitochondrial homeostasis …
Mitochondrial dysfunction pathway alterations offer potential biomarkers and therapeutic targets for ovarian cancer
L Shen, X Zhan - Oxidative Medicine and Cellular Longevity, 2022 - Wiley Online Library
The mitochondrion is a very versatile organelle that participates in some important cancer‐
associated biological processes, including energy metabolism, oxidative stress …
associated biological processes, including energy metabolism, oxidative stress …
PyInteraph2 and PyInKnife2 to analyze networks in protein structural ensembles
Due to the complex nature of noncovalent interactions and their long-range effects,
analyzing protein conformations using network theory can be enlightening. Protein Structure …
analyzing protein conformations using network theory can be enlightening. Protein Structure …
Modulation of the immunity and inflammation by autophagy
T Gan, S Qu, H Zhang, X Zhou - MedComm, 2023 - Wiley Online Library
Autophagy, a highly conserved cellular self‐degradation pathway, has emerged with novel
roles in the realms of immunity and inflammation. Genome‐wide association studies have …
roles in the realms of immunity and inflammation. Genome‐wide association studies have …