Despite the large number of immunomodulatory or immunosuppressive treatments available
to treat relapsing–remitting multiple sclerosis (MS), treatment of the progressive phase of the …

Progressive multiple sclerosis poses a considerable challenge in the evaluation of disease
progression and treatment response owing to its multifaceted pathophysiology. Traditional …

Background and Objectives Myelin and iron play essential roles in remyelination processes
of multiple sclerosis (MS) lesions. χ-separation, a novel biophysical model applied to …

The inability of the mammalian central nervous system (CNS) to undergo spontaneous
regeneration has long been regarded as a central tenet of neurobiology. However, while this …

Cortical myelin loss and repair in multiple sclerosis (MS) have been explored in
neuropathological studies, but the impact of these processes on neurodegeneration and the …

Objective Pathological studies suggest that multiple sclerosis (MS) lesions endure multiple
waves of damage and repair; however, the dynamics and characteristics of these processes …

History is full of women who made enormous contributions to science. While there is little to
no imbalance at the early career stage, a decreasing proportion of women is found as …

Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS) with
inflammatory and degenerative components affecting both the white (WM) and the grey …

Impact of highly active immunotherapy on acute and chronic neuroinflammation in
aggressive multiple sclerosis Page 1 1 UNIVERSITA’ DEGLI STUDI DI GENOVA Dottorato …