miRNAs as biomarkers in disease: latest findings regarding their role in diagnosis and prognosis
CE Condrat, DC Thompson, MG Barbu, OL Bugnar… - Cells, 2020 - mdpi.com
MicroRNAs (miRNAs) represent a class of small, non-coding RNAs with the main roles of
regulating mRNA through its degradation and adjusting protein levels. In recent years …
regulating mRNA through its degradation and adjusting protein levels. In recent years …
Integrating liquid biopsies into the management of cancer
During cancer progression and treatment, multiple subclonal populations of tumour cells
compete with one another, with selective pressures leading to the emergence of …
compete with one another, with selective pressures leading to the emergence of …
Exosomes and their roles in immune regulation and cancer
Exosomes, a subset of extracellular vesicles (EVs), function as a mode of intercellular
communication and molecular transfer. Exosomes facilitate the direct extracellular transfer of …
communication and molecular transfer. Exosomes facilitate the direct extracellular transfer of …
Circulating noncoding RNAs as biomarkers of cardiovascular disease and injury
J Viereck, T Thum - Circulation research, 2017 - Am Heart Assoc
The discovery of thousands of noncoding RNAs (ncRNAs) has expanded our view on
mammalian genomes and transcriptomes, as well as their organization and regulation …
mammalian genomes and transcriptomes, as well as their organization and regulation …
[HTML][HTML] Extracellular/circulating microRNAs: release mechanisms, functions and challenges
MH Sohel - Achievements in the Life Sciences, 2016 - Elsevier
MicroRNAs (miRNAs) are endogenously initiated, small non-coding RNAs and typically
regulate the expression of mRNAs in post transcriptional level either via translational …
regulate the expression of mRNAs in post transcriptional level either via translational …
Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles
Release of membrane vesicles, a process conserved in both prokaryotes and eukaryotes,
represents an evolutionary link, and suggests essential functions of a dynamic extracellular …
represents an evolutionary link, and suggests essential functions of a dynamic extracellular …
MicroRNA: biogenesis, function and role in cancer
LA MacFarlane, PR Murphy - Current genomics, 2010 - ingentaconnect.com
MicroRNAs are small, highly conserved non-coding RNA molecules involved in the
regulation of gene expression. MicroRNAs are transcribed by RNA polymerases II and III …
regulation of gene expression. MicroRNAs are transcribed by RNA polymerases II and III …
MicroRNAs in body fluids—the mix of hormones and biomarkers
MA Cortez, C Bueso-Ramos, J Ferdin… - Nature reviews Clinical …, 2011 - nature.com
Since the discovery of microRNAs (miRNAs), the study of these small noncoding RNAs has
steadily increased and more than 10,000 papers have already been published. The great …
steadily increased and more than 10,000 papers have already been published. The great …
Circulating microRNAs: novel biomarkers and extracellular communicators in cardiovascular disease?
EE Creemers, AJ Tijsen, YM Pinto - Circulation research, 2012 - Am Heart Assoc
In the past few years, the crucial role of different micro-RNAs (miRNAs) in the cardiovascular
system has been widely recognized. Recently, it was discovered that extracellular miRNAs …
system has been widely recognized. Recently, it was discovered that extracellular miRNAs …
Secretory mechanisms and intercellular transfer of microRNAs in living cells*♦
N Kosaka, H Iguchi, Y Yoshioka, F Takeshita… - Journal of Biological …, 2010 - ASBMB
The existence of circulating microRNAs (miRNAs) in the blood of cancer patients has raised
the possibility that miRNAs may serve as a novel diagnostic marker. However, the secretory …
the possibility that miRNAs may serve as a novel diagnostic marker. However, the secretory …