[HTML][HTML] Blue rubber bleb nevus (BRBN) syndrome is caused by somatic TEK (TIE2) mutations

J Soblet, J Kangas, M Nätynki, A Mendola… - Journal of Investigative …, 2017 - Elsevier
Blue rubber bleb nevus syndrome (Bean syndrome) is a rare, severe disorder of unknown
cause, characterized by numerous cutaneous and internal venous malformations; …

Sirolimus in blue rubber bleb naevus syndrome: A systematic review

XL Wong, K Phan… - … of paediatrics and …, 2019 - Wiley Online Library
The aim of this study is to review sirolimus as a treatment for blue rubber bleb naevus
syndrome (BRBNS). A literature search of Medline, Embase, CINAHL, SCOPUS and Google …

Long‐term sirolimus treatment in blue rubber bleb nevus syndrome: case report and review of the literature

D Weiss, A Teichler, PH Hoeger - Pediatric Dermatology, 2021 - Wiley Online Library
Blue rubber bleb nevus syndrome is a rare vascular syndrome characterized by continuous
eruption of vascular nodules in the skin, mucous membranes, and solid organs due to …

Response of blue rubber bleb nevus syndrome to sirolimus treatment

R Salloum, CE Fox, CR Alvarez‐Allende… - Pediatric blood & …, 2016 - Wiley Online Library
Background Blue rubber bleb nevus syndrome (BRBNS) is a rare multifocal venous
malformation syndrome involving predominantly the skin and gastrointestinal tract …

Diagnosis and management of children with Blue Rubber Bleb Nevus Syndrome: A multi-center case series

S Isoldi, D Belsha, I Yeop, A Uc, N Zevit… - Digestive and liver …, 2019 - Elsevier
Abstract Background Blue Rubber Bleb Nevus Syndrome (BRBNS) is a rare, severe,
sporadically occurring disorder characterized by multiple venous malformations. Aims To …

Successful management of blue rubber bleb nevus syndrome (BRBNS) with sirolimus

UO Ogu, G Abusin, RF Abu-Arja… - Case reports in …, 2018 - Wiley Online Library
Blue rubber bleb nevus syndrome (BRBNS) is a rare disease with vascular malformations in
several systems of the body, most commonly the skin and gastrointestinal tract. Bleeding …

Treatment options for gastrointestinal bleeding blue rubber bleb nevus syndrome: Systematic review

A Rimondi, A Sorge, A Murino, N Nandi… - Digestive …, 2024 - Wiley Online Library
Objectives Blue rubber bleb nevus syndrome (BRBNS) is a rare challenging cause of
gastrointestinal bleeding. We performed a systematic review of case reports and case series …

Sirolimus for management of GI bleeding in blue rubber bleb nevus syndrome: A case series

JT Duong, A Geddis, K Carlberg… - Pediatric Blood & …, 2022 - Wiley Online Library
Blue rubber bleb nevus syndrome (BRBNS) commonly presents with anemia from bleeding
gastrointestinal (GI) vascular malformations. Management is highly variable, as no …

[HTML][HTML] Sirolimus in the management of blue rubber bleb nevus syndrome: a case report and review of the literature

BM AlNooh, NG AlQadri, M Alghubayn… - Case Reports in …, 2021 - karger.com
Blue rubber bleb nevus syndrome (BRBNS) is a rare multifocal venous malformation (VM)
that may affect any tissue or organ but mainly affects the skin, subcutaneous tissue and …

Blue rubber bleb naevus syndrome: a rare cause of chronic occult blood loss and iron deficiency anaemia

MB Lybecker, M Stawowy, N Clausen - Case Reports, 2016 - casereports.bmj.com
Blue rubber bleb naevus syndrome (BRBNS) is a rare vascular disorder with malformed
veins, or blebs, appearing in the skin or internal organs. Gastrointestinal tract involvement is …