The expanding superfamily of phospholipase A2 enzymes: classification and characterization

DA Six, EA Dennis - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2000 - Elsevier
The phospholipase A2 (PLA2) superfamily consists of a broad range of enzymes defined by
their ability to catalyze the hydrolysis of the middle (sn-2) ester bond of substrate …

Scorpion venom components that affect ion-channels function

V Quintero-Hernández, JM Jiménez-Vargas… - Toxicon, 2013 - Elsevier
The number and types of venom components that affect ion-channel function are reviewed.
These are the most important venom components responsible for human intoxication …

Scorpion toxins specific for Na+‐channels

LD Possani, B Becerril, M Delepierre… - European journal of …, 1999 - Wiley Online Library
Na+‐channel specific scorpion toxins are peptides of 60–76 amino acid residues in length,
tightly bound by four disulfide bridges. The complete amino acid sequence of 85 distinct …

Peptides and genes coding for scorpion toxins that affect ion-channels

LD Possani, E Merino, M Corona, F Bolivar, B Becerril - Biochimie, 2000 - Elsevier
Most scorpion toxins are ligand peptides that recognize and bind to integral membrane
proteins known as ion-channels. To date there are at least 202 distinct sequences …

Scorpine, an anti‐malaria and anti‐bacterial agent purified from scorpion venom

R Conde, FZ Zamudio, MH Rodrı́guez… - FEBS letters, 2000 - Wiley Online Library
A novel peptide, scorpine, was isolated from the venom of the scorpion Pandinus imperator,
with anti‐bacterial activity and a potent inhibitory effect on the ookinete (ED50 0.7 μM) and …

Receptors for a growing family of secreted phospholipases A2

G Lambeau, M Lazdunski - Trends in pharmacological sciences, 1999 - cell.com
Abstract Phospholipases A 2 (PLA 2 s) are enzymes that catalyse the hydrolysis of the sn-2
acyl bond of glycerophospholipids to produce free fatty acids and lysophospholipids …

Increasing molecular diversity of secreted phospholipases A2 and their receptors and binding proteins

E Valentin, G Lambeau - Biochimica et Biophysica Acta (BBA)-Molecular …, 2000 - Elsevier
Secreted phospholipases A2 (sPLA2s) form a large family of structurally related enzymes
which are widespread in nature. Snake venoms are known for decades to contain a …

Hadrurin, a new antimicrobial peptide from the venom of the scorpion Hadrurus aztecus

A Torres‐Larios, GB Gurrola… - European journal of …, 2000 - Wiley Online Library
A new antimicrobial peptide, hadrurin, was isolated from the venom of the Mexican scorpion
Hadrurus aztecus, by gel filtration on a Sephadex G‐50 column, followed by high …

Diversity of peptide toxins from stinging ant venoms

SR Aili, A Touchard, P Escoubas, MP Padula, J Orivel… - Toxicon, 2014 - Elsevier
Abstract Ants (Hymenoptera: Formicidae) represent a taxonomically diverse group of
arthropods comprising nearly 13,000 extant species. Sixteen ant subfamilies have …

Novel human secreted phospholipase A2 with homology to the group III bee venom enzyme

E Valentin, F Ghomashchi, MH Gelb… - Journal of Biological …, 2000 - jbc.org
Venom and mammalian secreted phospholipases A 2 (sPLA 2 s) have been associated with
numerous physiological, pathological, and toxic processes. So far, structurally related group …