[HTML][HTML] Going below and beyond the surface: Microneedle structure, materials, drugs, fabrication, and applications for wound healing and tissue regeneration

S Lyu, Z Dong, X Xu, HP Bei, HY Yuen, CWJ Cheung… - Bioactive materials, 2023 - Elsevier
Microneedle, as a novel drug delivery system, has attracted widespread attention due to its
non-invasiveness, painless and simple administration, controllable drug delivery, and …

[HTML][HTML] Recent advances in long-acting drug delivery systems for anticancer drug

C Pacheco, A Baiao, T Ding, W Cui… - Advanced Drug Delivery …, 2023 - Elsevier
The use of systemic anticancer chemotherapy is intrinsically limited by its toxicity. Whether
dealing with small molecules or biopharmaceuticals, after systemic administration, small …

A microneedle vaccine printer for thermostable COVID-19 mRNA vaccines

A Vander Straeten, M Sarmadi, JL Daristotle… - Nature …, 2024 - nature.com
Decentralized manufacture of thermostable mRNA vaccines in a microneedle patch (MNP)
format could enhance vaccine access in low-resource communities by eliminating the need …

[HTML][HTML] A comprehensive review of microneedles: Types, materials, processes, characterizations and applications

FK Aldawood, A Andar, S Desai - Polymers, 2021 - mdpi.com
Drug delivery through the skin offers many advantages such as avoidance of hepatic first-
pass metabolism, maintenance of steady plasma concentration, safety, and compliance over …

Microneedle for transdermal drug delivery: current trends and fabrication

JH Jung, SG ** - Journal of pharmaceutical investigation, 2021 - Springer
Background Transdermal delivery has the advantage of bypassing the first-pass effect and
allowing sustained release of the drug. However, the drug delivery is limited owing to the …

High-resolution two-photon polymerization: the most versatile technique for the fabrication of microneedle arrays

Z Faraji Rad, PD Prewett, GJ Davies - Microsystems & nanoengineering, 2021 - nature.com
Microneedle patches have received much interest in the last two decades as drug/vaccine
delivery or fluid sampling systems for diagnostic and monitoring purposes. Microneedles are …

Microneedle array delivered recombinant coronavirus vaccines: Immunogenicity and rapid translational development

E Kim, G Erdos, S Huang, TW Kenniston, SC Balmert… - …, 2020 - thelancet.com
Background Coronaviruses pose a serious threat to global health as evidenced by Severe
Acute Respiratory Syndrome (SARS), Middle East Respiratory Syndrome (MERS), and …

Microneedle-mediated transdermal delivery of biopharmaceuticals

HX Nguyen, CN Nguyen - Pharmaceutics, 2023 - mdpi.com
Transdermal delivery provides numerous benefits over conventional routes of
administration. However, this strategy is generally limited to a few molecules with specific …

[HTML][HTML] Recent advances of microneedles for biomedical applications: drug delivery and beyond

J Yang, X Liu, Y Fu, Y Song - Acta Pharmaceutica Sinica B, 2019 - Elsevier
The microneedle (MN), a highly efficient and versatile device, has attracted extensive
scientific and industrial interests in the past decades due to prominent properties including …

[HTML][HTML] Microneedle arrays as transdermal and intradermal drug delivery systems: Materials science, manufacture and commercial development

E Larrañeta, REM Lutton, AD Woolfson… - Materials Science and …, 2016 - Elsevier
Transdermal drug delivery offers a number of advantages for the patient, due not only its non-
invasive and convenient nature, but also factors such as avoidance of first pass metabolism …