Electrochemotherapy: from the drawing board into medical practice

D Miklavčič, B Mali, B Kos, R Heller, G Serša - Biomedical engineering …, 2014 - Springer
Electrochemotherapy is a local treatment of cancer employing electric pulses to improve
transmembrane transfer of cytotoxic drugs. In this paper we discuss electrochemotherapy …

Electrochemotherapy–Emerging applications technical advances, new indications, combined approaches, and multi-institutional collaboration

LG Campana, I Edhemovic, D Soden… - European Journal of …, 2019 - Elsevier
The treatment of tumors with electrochemotherapy (ECT) has surged over the past decade.
Thanks to the transient cell membrane permeabilization induced by the short electric pulses …

State-of-the-art pulsed field ablation for cardiac arrhythmias: ongoing evolution and future perspective

KRJ Chun, D Miklavčič, K Vlachos, S Bordignon… - Europace, 2024 - academic.oup.com
Pulsed field ablation (PFA) is an innovative approach in the field of cardiac
electrophysiology aimed at treating cardiac arrhythmias. Unlike traditional catheter ablation …

Antitumor effectiveness of electrochemotherapy: a systematic review and meta-analysis

B Mali, T Jarm, M Snoj, G Sersa, D Miklavcic - european Journal of surgical …, 2013 - Elsevier
BACKGROUND: This systematic review has two purposes: to consolidate the current
knowledge about clinical effectiveness of electrochemotherapy, a highly effective local …

Electrochemotherapy as a new modality in interventional oncology: a review

U Probst, I Fuhrmann, L Beyer… - Technology in cancer …, 2018 - journals.sagepub.com
Electroporation is a well-known phenomenon that occurs at the cell membrane when cells
are exposed to high-intensity electric pulses. Depending on electric pulse amplitude and …

Electrochemotherapy: technological advancements for efficient electroporation-based treatment of internal tumors

D Miklavčič, G Serša, E Brecelj, J Gehl… - Medical & biological …, 2012 - Springer
Electrochemotherapy, a combination of high voltage electric pulses and of an anticancer
drug, has been demonstrated to be highly effective in treatment of cutaneous and …

Modeling of electric field distribution in tissues during electroporation

S Corovic, I Lackovic, P Sustaric, T Sustar… - Biomedical engineering …, 2013 - Springer
Background Electroporation based therapies and treatments (eg electrochemotherapy, gene
electrotransfer for gene therapy and DNA vaccination, tissue ablation with irreversible …

Electrochemotherapy of superficial tumors–Current status:: Basic principles, operating procedures, shared indications, and emerging applications

LG Campana, D Miklavčič, G Bertino, R Marconato… - Seminars in …, 2019 - Elsevier
Abstract Treatment of superficial tumors with electrochemotherapy (ECT) has shown a steep
rise over the past decade and indications range from skin cancers to locally advanced or …

A numerical investigation of the electric and thermal cell kill distributions in electroporation-based therapies in tissue

PA Garcia, RV Davalos, D Miklavcic - PloS one, 2014 - journals.plos.org
Electroporation-based therapies are powerful biotechnological tools for enhancing the
delivery of exogeneous agents or killing tissue with pulsed electric fields (PEFs) …

Electrochemotherapy with bleomycin induces hallmarks of immunogenic cell death in murine colon cancer cells

CY Calvet, D Famin, FM André, LM Mir - Oncoimmunology, 2014 - Taylor & Francis
Electrochemotherapy (ECT) is a local cancer treatment that has been used over the course
of more than 2 decades for the removal of cutaneous and subcutaneous tumors. Several …