DNA origami has emerged as a powerful method to generate DNA nanostructures with
dynamic properties and nanoscale control. These nanostructures enable complex …

Biological materials are self-assembled with near-atomic precision in living cells, whereas
synthetic 3D structures generally lack such precision and controllability. Recently, DNA …

Vaccines are the key technology to combat existing and emerging infectious diseases.
However, increasing the potency, quality and durability of the vaccine response remains a …

Therapies modulating the immune system offer the prospect of treating a wide range of
conditions including infectious diseases, cancer and autoimmunity. Biomaterials can …

Nucleic acids, including deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), are
natural biopolymers composed of nucleotides that store, transmit, and express genetic …

DNA origami may enable more versatile gene delivery applications through its ability to
create custom nanoscale objects with specific targeting, cell-invading, and intracellular …

Defending against future pandemics requires vaccine platforms that protect across a range
of related pathogens. Nanoscale patterning can be used to address this issue. Here, we …

Modern vaccine design has sought a minimalization approach, moving to the isolation of
antigens from pathogens that invoke a strong neutralizing immune response. This approach …

Insulin binds the insulin receptor (IR) and regulates anabolic processes in target tissues.
Impaired IR signalling is associated with multiple diseases, including diabetes, cancer and …

DNA nanostructures have played an important role in the development of novel drug
delivery systems. Herein, we report a DNA origami‐based CRISPR/Cas9 gene editing …