Cellular Phenotype and Apoptosis: The function of epithelial tissues is the protection of the
organism from chemical, microbial, and physical challenges which is indispensable for …

Multicellular organisms are separated from the external environment by a layer of epithelial
cells whose integrity is maintained by intercellular junctional complexes composed of tight …

The global emergency caused by the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) pandemic can only be solved with effective and widespread preventive and …

Airway epithelial cells form a barrier to the outside world and are at the front line of mucosal
immunity. Epithelial apical junctional complexes are multiprotein subunits that promote cell …

Adenoviruses have been studied intensively for over 50 years as models of virus–cell
interactions and latterly as gene vectors. With the advent of more sophisticated structural …

We have identified desmoglein-2 (DSG-2) as the primary high-affinity receptor used by
adenoviruses Ad3, Ad7, Ad11 and Ad14. These serotypes represent key human pathogens …

Tight junctions contribute to the paracellular barrier, the fence dividing plasma membranes,
and signal transduction, acting as a multifunctional complex in vertebrate epithelial and …

Group B coxsackieviruses (CVBs) must cross the epithelium as they initiate infection, but the
mechanism by which this occurs remains uncertain. The coxsackievirus and adenovirus …

Pathogen entry into cells occurs by direct penetration of the plasma membrane, clathrin‐
mediated endocytosis, caveolar endocytosis, pinocytosis or macropinocytosis. For a …

The epithelial barrier is a critical border that segregates luminal material from entering
tissues. Essential components of this epithelial fence are physical intercellular structures …