Psychedelic drugs: neurobiology and potential for treatment of psychiatric disorders

FX Vollenweider, KH Preller - Nature Reviews Neuroscience, 2020‏ - nature.com
Renewed interest in the use of psychedelics in the treatment of psychiatric disorders
warrants a better understanding of the neurobiological mechanisms underlying the effects of …

Molecular mechanisms underlying the antidepressant actions of arketamine: beyond the NMDA receptor

Y Wei, L Chang, K Hashimoto - Molecular psychiatry, 2022‏ - nature.com
The discovery of robust antidepressant actions exerted by the N-methyl-D-aspartate receptor
(NMDAR) antagonist (R, S)-ketamine has been a crucial breakthrough in mood disorder …

Treatment‐resistant depression: definition, prevalence, detection, management, and investigational interventions

RS McIntyre, M Alsuwaidan, BT Baune, M Berk… - World …, 2023‏ - Wiley Online Library
Treatment‐resistant depression (TRD) is common and associated with multiple serious
public health implications. A consensus definition of TRD with demonstrated predictive utility …

Connectome gradient dysfunction in major depression and its association with gene expression profiles and treatment outcomes

M **a, J Liu, A Mechelli, X Sun, Q Ma, X Wang… - Molecular …, 2022‏ - nature.com
Patients with major depressive disorder (MDD) exhibit concurrent deficits in both sensory
and higher-order cognitive processing. Connectome studies have suggested a principal …

Adhesive and hydrophobic bilayer hydrogel enabled on‐skin biosensors for high‐fidelity classification of human emotion

G Yang, K Zhu, W Guo, D Wu, X Quan… - Advanced Functional …, 2022‏ - Wiley Online Library
Traditional human emotion recognition is based on electroencephalogram (EEG) data
collection technologies which rely on plenty of rigid electrodes and lack anti‐interference …

The C Factor: Cognitive dysfunction as a transdiagnostic dimension in psychopathology

A Abramovitch, T Short, A Schweiger - Clinical Psychology Review, 2021‏ - Elsevier
Research into cognitive functions across psychological disorders suggests that cognitive
deficiencies may be present across multiple disorders, potentially pointing to a …

Protein misfolding and amyloid nucleation through liquid–liquid phase separation

S Mukherjee, M Poudyal, K Dave, P Kadu… - Chemical Society …, 2024‏ - pubs.rsc.org
Liquid–liquid phase separation (LLPS) is an emerging phenomenon in cell physiology and
diseases. The weak multivalent interaction prerequisite for LLPS is believed to be facilitated …

PTSD symptoms among health workers and public service providers during the COVID-19 outbreak

SU Johnson, OV Ebrahimi, A Hoffart - PloS one, 2020‏ - journals.plos.org
In the frontline of the pandemic stand healthcare workers and public service providers,
occupations which have proven to be associated with increased mental health problems …

Cognitive impairment in depression: recent advances and novel treatments

G Perini, M Cotta Ramusino, E Sinforiani… - Neuropsychiatric …, 2019‏ - Taylor & Francis
In the past, little or no attention was paid to cognitive disorders associated with depression
(a condition sometimes termed pseudodementia). However, recent years have seen a …

The clinical characterization of the adult patient with depression aimed at personalization of management

M Maj, DJ Stein, G Parker, M Zimmerman… - World …, 2020‏ - Wiley Online Library
Depression is widely acknowledged to be a heterogeneous entity, and the need to further
characterize the individual patient who has received this diagnosis in order to personalize …