Crop production systems need to expand their outputs sustainably to feed a burgeoning
human population. Advances in genome sequencing technologies combined with efficient …

This review article summarizes 20 years of our research on hepatic stellate cells within the
framework of two collaborative research centers CRC575 and CRC974 at the Heinrich …

Motivation Dynamic models are used in systems biology to study and understand cellular
processes like gene regulation or signal transduction. Frequently, ordinary differential …

A plethora of studies have uncovered numerous important genes with agricultural
significance in staple crops. However, when it comes to orphan crops like minor millet …

Survival or apoptosis is a binary decision in individual cells. However, at the cell-population
level, a graded increase in survival of colony-forming unit-erythroid (CFU-E) cells is …

Likelihood ratios are frequently utilized as basis for statistical tests, for model selection
criteria and for assessing parameter and prediction uncertainties, eg using the profile …

Mathematical biology has made significant contributions and advancements in the biological
sciences. Recruitment efforts focus on encouraging students, especially those who are …

Motivation: Metabolic kinetic models are widely used to model biological systems. Despite
their widespread use, it remains challenging to parameterize these Ordinary Differential …

Motivation In systems biology, the analysis of complex nonlinear systems faces many
methodological challenges. However, the performance evaluation of competing methods is …

The success of physics in the endeavor of understanding the natural world is based on the
ability to formulate the laws of nature in the language of mathematics. Not only allow …