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Acute stroke intervention: a systematic review
S Prabhakaran, I Ruff, RA Bernstein - Jama, 2015 - jamanetwork.com
Importance Acute ischemic stroke is a major cause of mortality and morbidity in the United
States. We review the latest data and evidence supporting catheter-directed treatment for …
States. We review the latest data and evidence supporting catheter-directed treatment for …
Power failure: why small sample size undermines the reliability of neuroscience
KS Button, JPA Ioannidis, C Mokrysz… - Nature reviews …, 2013 - nature.com
A study with low statistical power has a reduced chance of detecting a true effect, but it is
less well appreciated that low power also reduces the likelihood that a statistically significant …
less well appreciated that low power also reduces the likelihood that a statistically significant …
Colchicine in acute myocardial infarction
SS Jolly, MA d'Entremont, SF Lee, R Mian… - … England Journal of …, 2025 - Mass Medical Soc
Background Inflammation is associated with adverse cardiovascular events. Data from
recent trials suggest that colchicine reduces the risk of cardiovascular events. Methods In …
recent trials suggest that colchicine reduces the risk of cardiovascular events. Methods In …
Defibrillation strategies for refractory ventricular fibrillation
S Cheskes, PR Verbeek, IR Drennan… - … England Journal of …, 2022 - Mass Medical Soc
Background Despite advances in defibrillation technology, shock-refractory ventricular
fibrillation remains common during out-of-hospital cardiac arrest. Double sequential external …
fibrillation remains common during out-of-hospital cardiac arrest. Double sequential external …
Guidelines for reporting trial protocols and completed trials modified due to the COVID-19 pandemic and other extenuating circumstances: the CONSERVE 2021 …
AM Orkin, PJ Gill, D Ghersi, L Campbell, J Sugarman… - Jama, 2021 - jamanetwork.com
Importance Extenuating circumstances can trigger unplanned changes to randomized trials
and introduce methodological, ethical, feasibility, and analytical challenges that can …
and introduce methodological, ethical, feasibility, and analytical challenges that can …
Bevacizumab for newly diagnosed pleural mesothelioma in the Mesothelioma Avastin Cisplatin Pemetrexed Study (MAPS): a randomised, controlled, open-label …
G Zalcman, J Mazieres, J Margery, L Greillier… - The Lancet, 2016 - thelancet.com
Background Malignant pleural mesothelioma is an aggressive cancer with poor prognosis,
linked to occupational asbestos exposure. Vascular endothelial growth factor is a key …
linked to occupational asbestos exposure. Vascular endothelial growth factor is a key …
Active learning increases student performance in science, engineering, and mathematics
S Freeman, SL Eddy, M McDonough, MK Smith… - Proceedings of the …, 2014 - pnas.org
To test the hypothesis that lecturing maximizes learning and course performance, we
metaanalyzed 225 studies that reported data on examination scores or failure rates when …
metaanalyzed 225 studies that reported data on examination scores or failure rates when …
AGA clinical practice guideline on fecal microbiota–based therapies for select gastrointestinal diseases
Background & Aims Fecal microbiota–based therapies include conventional fecal microbiota
transplant and US Food and Drug Administration–approved therapies, fecal microbiota live …
transplant and US Food and Drug Administration–approved therapies, fecal microbiota live …
Surgery for weight loss in adults
JL Colquitt, K Pickett, E Loveman… - Cochrane database of …, 2014 - cochranelibrary.com
Background Bariatric (weight loss) surgery for obesity is considered when other treatments
have failed. The effects of the available bariatric procedures compared with medical …
have failed. The effects of the available bariatric procedures compared with medical …
Industry sponsorship and research outcome
Background Clinical research affecting how doctors practice medicine is increasingly
sponsored by companies that make drugs and medical devices. Previous systematic …
sponsored by companies that make drugs and medical devices. Previous systematic …