Legume-derived bioactive peptides: Role in cardiovascular disease prevention and control

DF Hernandez, L Mojica, EG de Mejia - Current Opinion in Food Science, 2024 - Elsevier
Highlights•Legume-derived peptides can reduce cardiovascular disease
progression.•Bioactive peptides activate novel pathways for cardiovascular disease …

Regulation of cholesterol homeostasis in osteoporosis mechanisms and therapeutics

C Bao, T Wu, S Zhu, X Wang, Y Zhang, X Wang… - Clinical …, 2023 - portlandpress.com
Osteoporosis is a metabolic bone disease that affects hundreds of millions of people
worldwide and is characterized by excessive loss of bone protein and mineral content. The …

Hawthorn leaf flavonoids alleviate the deterioration of atherosclerosis by inhibiting SCAP-SREBP2-LDLR pathway through sPLA2-ⅡA signaling in macrophages in …

X Bai, S Wang, L Shu, Q Cao, H Hu, Y Zhu… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Hawthorn leaves are a combination of the dried leaves of
the Rosaceae plants, ie, Crataegus pinnatifida Bge. or Crataegus pinnatifida Bge. var. major …

[HTML][HTML] Unravelling the molecular mechanisms associated with the role of food-derived bioactive peptides in promoting cardiovascular health

SM Martínez-Sánchez, JA Gabaldón-Hernández… - Journal of Functional …, 2020 - Elsevier
Food-derived bioactive peptides (BPs) are nutritionally and functionally important for
regulating some physiological functions in the body; however, there is little information on …

[HTML][HTML] Food-derived peptides with inhibitory capacity for HMG-CoA reductase activity: a potential nutraceutical for hypercholesterolemia

G Santos-Sánchez, AI Álvarez-López… - Food Science and …, 2024 - Elsevier
Cardiovascular diseases (CVDs) are the leading global cause of mortality and disease
burden. Statins are the most prescribed lipid-lowering drugs to treat hypercholesterolemia …

[HTML][HTML] Food-derived peptides with hypocholesterolemic activity: Production, transepithelial transport and cellular mechanisms

J Li, C Bollati, L d'Adduzio, M Fanzaga… - Trends in Food Science …, 2024 - Elsevier
Background In recent years, food-derived peptides have gained much attention for their
potential health benefits. Some short and medium-sized peptides released from food …

IAF, QGF, and QDF peptides exhibit cholesterol-lowering activity through a statin-like HMG-CoA reductase regulation mechanism: In silico and in vitro approach

M Silva, B Philadelpho, J Santos, V Souza… - International Journal of …, 2021 - mdpi.com
In this study, in silico approaches are employed to investigate the binding mechanism of
peptides derived from cowpea β-vignin and HMG-CoA reductase. With the obtained …

Olive (Olea europaea L.) Seed as New Source of Cholesterol-Lowering Bioactive Peptides: Elucidation of Their Mechanism of Action in HepG2 Cells and Their Trans …

M Bartolomei, J Li, AL Capriotti, M Fanzaga… - Nutrients, 2024 - mdpi.com
The production of olive oil has important economic repercussions in Mediterranean
countries but also a considerable impact on the environment. This production generates …

The modulatory effects on enterohepatic cholesterol metabolism of novel cholesterol-lowering peptides from gastrointestinal digestion of Xuanwei ham

J Guo, Y Wang, P Li, W Wu, F Xu, K Zhou… - Food Research …, 2023 - Elsevier
The aim of this study was to investigate the effects and mechanism of in vitro protein
digestive products of Xuanwei ham with different ripening periods on cholesterol metabolism …

Hypocholesterolemic effect of potent peptide and bioactive fraction from pigeon pea by-products in Wistar rats

V Kumar, SP Muthu Kumar, PK Tiku - International Journal of Peptide …, 2021 - Springer
Elevation high plasma cholesterol plays a significant role in promoting the incidence of
atherosclerosis and coronary heart disease. In the current study, a high cholesterol diet …