Migrating Schwann cells direct axon regeneration within the peripheral nerve bridge

Q Min, DB Parkinson, XP Dun - Glia, 2021 - Wiley Online Library
Schwann cells within the peripheral nervous system possess a remarkable regenerative
potential. Current research shows that peripheral nerve‐associated Schwann cells possess …

Cortical connectivity and sensory coding

KD Harris, TD Mrsic-Flogel - Nature, 2013 - nature.com
The sensory cortex contains a wide array of neuronal types, which are connected together
into complex but partially stereotyped circuits. Sensory stimuli trigger cascades of electrical …

[HTML][HTML] A high-resolution transcriptomic and spatial atlas of cell types in the whole mouse brain

Z Yao, CTJ van Velthoven, M Kunst, M Zhang… - Nature, 2023 - nature.com
The mammalian brain consists of millions to billions of cells that are organized into many cell
types with specific spatial distribution patterns and structural and functional properties …

[HTML][HTML] Molecular architecture of the mouse nervous system

A Zeisel, H Hochgerner, P Lönnerberg, A Johnsson… - Cell, 2018 - cell.com
The mammalian nervous system executes complex behaviors controlled by specialized,
precisely positioned, and interacting cell types. Here, we used RNA sequencing of half a …

[HTML][HTML] Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity

K Hezaveh, RS Shinde, A Klötgen, MJ Halaby… - Immunity, 2022 - cell.com
The aryl hydrocarbon receptor (AhR) is a sensor of products of tryptophan metabolism and a
potent modulator of immunity. Here, we examined the impact of AhR in tumor-associated …

Combinatorial design of nanoparticles for pulmonary mRNA delivery and genome editing

B Li, RS Manan, SQ Liang, A Gordon, A Jiang… - Nature …, 2023 - nature.com
The expanding applications of nonviral genomic medicines in the lung remain restricted by
delivery challenges. Here, leveraging a high-throughput platform, we synthesize and screen …

The Allen mouse brain common coordinate framework: a 3D reference atlas

Q Wang, SL Ding, Y Li, J Royall, D Feng, P Lesnar… - Cell, 2020 - cell.com
Recent large-scale collaborations are generating major surveys of cell types and
connections in the mouse brain, collecting large amounts of data across modalities, spatial …

A molecular cell atlas of the human lung from single-cell RNA sequencing

KJ Travaglini, AN Nabhan, L Penland, R Sinha… - Nature, 2020 - nature.com
Although single-cell RNA sequencing studies have begun to provide compendia of cell
expression profiles,,,,,,,–, it has been difficult to systematically identify and localize all …

A network of macrophages supports mitochondrial homeostasis in the heart

JA Nicolás-Ávila, AV Lechuga-Vieco… - Cell, 2020 - cell.com
Cardiomyocytes are subjected to the intense mechanical stress and metabolic demands of
the beating heart. It is unclear whether these cells, which are long-lived and rarely renew …

Distinct contributions of partial and full EMT to breast cancer malignancy

F Lüönd, N Sugiyama, R Bill, L Bornes, C Hager… - Developmental cell, 2021 - cell.com
Epithelial-mesenchymal transition (EMT) is a transient, reversible process of cell de-
differentiation where cancer cells transit between various stages of an EMT continuum …