Post hepatectomy liver failure (PHLF)–recent advances in prevention and clinical management

JA Søreide, R Deshpande - European Journal of Surgical Oncology, 2021 - Elsevier
Background Posthepatectomy liver failure (PHLF) is a relatively rare but feared complication
following liver surgery, and associated with high morbidity, mortality and cost implications …

Hepatobiliary cancers, version 2.2021, NCCN clinical practice guidelines in oncology

AB Benson, MI D'Angelica, DE Abbott… - Journal of the National …, 2021 - jnccn.org
The NCCN Guidelines for Hepatobiliary Cancers focus on the screening, diagnosis, staging,
treatment, and management of hepatocellular carcinoma (HCC), gallbladder cancer, and …

How much remnant is enough in liver resection?

A Guglielmi, A Ruzzenente, S Conci… - Digestive surgery, 2012 - karger.com
Background: Liver resection represents the first choice of treatment for primary and
secondary liver malignancies, offering the patient the best chance of long-term survival. The …

Posthepatectomy liver failure: a definition and grading by the International Study Group of Liver Surgery (ISGLS)

NN Rahbari, OJ Garden, R Padbury, M Brooke-Smith… - Surgery, 2011 - Elsevier
BACKGROUND: Posthepatectomy liver failure is a feared complication after hepatic
resection and a major cause of perioperative mortality. There is currently no standardized …

Right portal vein ligation combined with in situ splitting induces rapid left lateral liver lobe hypertrophy enabling 2-staged extended right hepatic resection in small-for …

AA Schnitzbauer, SA Lang, H Goessmann… - Annals of …, 2012 - journals.lww.com
Objective: To evaluate a new 2-step technique for obtaining adequate but short-term
parenchymal hypertrophy in oncologic patients requiring extended right hepatic resection …

ALPPS versus portal vein embolization for hepatitis-related hepatocellular carcinoma: a changing paradigm in modulation of future liver remnant before major …

A Chan, WY Zhang, K Chok, J Dai, R Ji, C Kwan… - Annals of …, 2021 - journals.lww.com
Objective: The aim of this study was to evaluate the short-and long-term outcome of
associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) for …

High survival rate after two-stage resection of advanced colorectal liver metastases: response-based selection and complete resection define outcome

A Brouquet, EK Abdalla, S Kopetz… - Journal of clinical …, 2011 - ascopubs.org
Purpose Prolonged survival after two-stage resection (TSR) of advanced colorectal liver
metastases (CLM) may be the result of selection of best responders to chemotherapy. The …

RAS mutation clinical risk score to predict survival after resection of colorectal liver metastases

KW Brudvik, RP Jones, F Giuliante, J Shindoh… - Annals of …, 2019 - journals.lww.com
Objective: To determine the impact of RAS mutation status on the traditional clinical score (t-
CS) to predict survival after resection of colorectal liver metastases (CLM). Background: The …

Mutation Status of RAS, TP53, and SMAD4 is Superior to Mutation Status of RAS Alone for Predicting Prognosis after Resection of Colorectal Liver Metastases

Y Kawaguchi, S Kopetz, TE Newhook, M De Bellis… - Clinical Cancer …, 2019 - AACR
Purpose: Somatic gene mutations have been increasingly recognized to impact prognosis
following resection of colorectal liver metastases (CLM). We aimed to determine the impact …

Current evidence on posthepatectomy liver failure: comprehensive review

E Sparrelid, PB Olthof, BVM Dasari, JI Erdmann… - BJS open, 2022 - academic.oup.com
Introduction Despite important advances in many areas of hepatobiliary surgical practice
during the past decades, posthepatectomy liver failure (PHLF) still represents an important …