Chemistry of organometallic nucleic acid components: personal perspectives and prospects for the future

M Klarek, K Kowalski - Dalton Transactions, 2024 - pubs.rsc.org
Organometallic modifications of biologically important compounds such as drugs, secondary
natural products, peptides, and nucleic acids, to name just a few, represent a well …

Tuning optical absorption and emission using strongly coupled dimers in programmable DNA scaffolds

SM Hart, X Wang, J Guo, M Bathe… - The Journal of …, 2022 - ACS Publications
Molecular materials for light harvesting, computing, and fluorescence imaging require
nanoscale integration of electronically active subunits. Variation in the optical absorption …

Tuning DNA supramolecular polymers by the addition of small, functionalized nucleobase mimics

C Lachance-Brais, CD Hennecker… - Journal of the …, 2021 - ACS Publications
Nucleobase mimicking small molecules able to reconfigure DNA are a recently discovered
strategy that promises to extend the structural and functional diversity of nucleic acids …

Synthesis of complex molecular systems—The foreseen role of organic chemists

T Schnitzer, G Vantomme - ACS Central Science, 2020 - ACS Publications
How to control the self-assembly of complex molecular systems is unknown. Yet, these
complex molecular systems are fundamental for advances in material and biomedical …

Structural basis for targeting T: T mismatch with triaminotriazine-acridine conjugate induces a U-shaped head-to-head four-way junction in CTG repeat DNA

CM Chien, PC Wu, R Satange, CC Chang… - Journal of the …, 2020 - ACS Publications
The potent DNA-binding compound triaminotriazine-acridine conjugate (Z1) functions by
targeting T: T mismatches in CTG trinucleotide repeats that are responsible for causing …

The unusual structural properties and potential biological relevance of switchback DNA

BR Madhanagopal, H Talbot, A Rodriguez… - Nature …, 2024 - nature.com
Synthetic DNA motifs form the basis of nucleic acid nanotechnology. The biochemical and
biophysical properties of these motifs determine their applications. Here, we present a …

Metal-responsive reversible binding of triplex-forming oligonucleotides with 5-hydroxyuracil nucleobases

K Nishiyama, K Mori, Y Takezawa… - Chemical …, 2021 - pubs.rsc.org
Metal-responsive triplex-forming oligonucleotides (TFOs) were synthesised by incorporating
5-hydroxyuracil (UOH) nucleobases as metal recognition sites. Binding of the UOH …

Supramolecular Chemistry: Exploring the Use of Electronic Structure, Molecular Dynamics, and Machine Learning Approaches

MC Colaço, VA Glitz, AK Jacobs… - European Journal of …, 2024 - Wiley Online Library
This review aims to highlight the role that computational chemistry has played in advancing
the supramolecular chemistry field. We demonstrated recent uses of computational …

Bipyridine‐Modified DNA Three‐Way Junctions with Amide linkers: Metal‐Dependent Structure Induction and Self‐Sorting

Y Takezawa, S Sakakibara… - Chemistry–A European …, 2021 - Wiley Online Library
DNA three‐way junction (3WJ) structures are essential building blocks for the construction of
DNA nanoarchitectures. We have synthesized a bipyridine (bpy)‐modified DNA 3WJ by …

Light-induced formation of silver (I)-mediated base pairs in DNA: Possibilities and limitations

S Naskar, M Hebenbrock, J Müller - Inorganica Chimica Acta, 2020 - Elsevier
The applicability of the caged nucleoside C NPP (2′-deoxycytidine bearing an ortho-
nitrophenylpropyl group at the exocyclic N4 position) in the light-triggered formation of three …