Development of copper based drugs, radiopharmaceuticals and medical materials

P Szymański, T Frączek, M Markowicz… - Biometals, 2012 - Springer
Copper is one of the most interesting elements for various biomedical applications. Copper
compounds show vast array of biological actions, including anti-inflammatory, anti …

Recent progress in anticonvulsant drug research: strategies for anticonvulsant drug development and applications of antiepileptic drugs for non-epileptic central …

S Dalkara, A Karakurt - Current topics in medicinal chemistry, 2012 - ingentaconnect.com
Major advances in antiepileptic drug therapy have taken place since 1950s. In the first
period, several antiepileptic drugs (AEDs) such as phenobarbital, diphenylhydantoin …

Synthesis, crystal structure, spectroscopic properties and potential biological activities of salicylate‒neocuproine ternary copper (II) complexes

L Kucková, K Jomová, A Švorcová, M Valko, P Segľa… - Molecules, 2015 - mdpi.com
Mixed ligand copper (II) complexes containing derivatives of salicylic acid and heterocyclic
ligands with nitrogen donor atoms have been the subject of various studies and reviews. In …

Spectrophotometric determination of trace concentrations of copper in waters using the chromogenic reagent 4-amino-3-mercapto-6-[2-(2-thienyl) vinyl]-1, 2, 4-triazin …

SS Alharthi, HM Al-Saidi - Applied Sciences, 2020 - mdpi.com
A simple, selective, and inexpensive spectrophotometric method is described in the present
study for estimation of trace concentrations of Cu2+ in water based on its reaction with …

Efficient synthesis and evaluation of bis-pyridinium/bis-quinolinium metallosalophens as antibiotic and antitumor candidates

RFM Elshaarawy, IM Eldeen, EM Hassan - Journal of Molecular Structure, 2017 - Elsevier
Inspired with the pharmacological diversity of salophens and in our endeavor to explore a
new strategy which may conflict the invasion of drug resistance, we report herein efficient …

New mixed ligand zinc (II) complexes based on the antiepileptic drug sodium valproate and bioactive nitrogen-donor ligands. Synthesis, structure and biological …

M Darawsheh, HA Ali, AL Abuhijleh… - European journal of …, 2014 - Elsevier
Starting from the precursor [Zinc Valproate complex](1), new mixed ligand zinc (II)
complexes of valproic acid and nitrogen-based ligands, formulating as,[Zn (valp) 2 2, 9 …

Bridging the gap between theory and treatment: Transition metal complexes as successful candidates in medicine

S Abdolmaleki, A Aliabadi, S Khaksar - Coordination Chemistry Reviews, 2025 - Elsevier
Transition metal complexes are a versatile area of research in the fields of chemistry,
biochemistry, and medicine. Their unique electronic properties, reactivity patterns, and …

Comparison of spectral and thermal properties and antibacterial activity of new binary and ternary complexes of Sm (III), Eu (III) and Gd (III) ions with N …

L Zapała, M Kosińska, E Woźnicka, Ł Byczyński… - Thermochimica …, 2019 - Elsevier
New binuclear binary and ternary complexes of Sm (III), Eu (III), and Gd (III) ions with N-
phenylanthranilic acid and 1, 10-phenanthroline were obtained in solid phase and …

New mixed ligand palladium (II) complexes based on the antiepileptic drug sodium valproate and bioactive nitrogen-donor ligands: Synthesis, structural …

L Tabrizi, H Chiniforoshan, H Tavakol - Spectrochimica Acta Part A …, 2015 - Elsevier
Abstract The complexes [Pd (valp) 2 (imidazole) 2](1),[Pd (valp) 2 (pyrazine) 2](2)(valp is
sodium valproate) have been synthesized and characterized using IR, 1 H NMR, 13 C {1 H} …

Cytotoxicity, genotoxicity and mutagenicity of mixed ternary mononuclear Mg complex based on valproic acid with 1,10‐phenanthroline in Saccharomyces cerevisiae …

J Vanini, GB Rodrigues, ALM Juchem… - Basic & Clinical …, 2024 - Wiley Online Library
Valproic acid (VA) is a widely used drug for the treatment of diseases affecting the central
nervous system. Due to its epigenetic modulatory potential, it has been studied for possible …