The incidence of dementia and cardiovascular disease (CVD) increases with age. Current
evidence supports the role for both atherosclerosis and arteriosclerosis as a common …

For decades, the hypothesis that brain deposition of the amyloid β protein initiates
Alzheimer's disease has dominated research and clinical trials. Targeting amyloid β is …

Importance Midlife vascular risk factors have been associated with late-life dementia.
Whether these risk factors directly contribute to brain amyloid deposition is less well …

Importance Although suicide is a leading cause of death for children in the United States,
and the rate of suicide in childhood has steadily increased, little is known about suicidal …

Background—Studies have linked midlife and late-life cardiovascular risk factors (CVRFs) to
cognitive function, yet little is known about CVRF exposure in early adulthood and …

Background: In adults, high blood pressure (BP), adverse serum lipids, and smoking
associate with cognitive deficits. The effects of these risk factors from childhood on midlife …

Alzheimer's Disease (AD) and atherosclerosis remain two of the largest public health
burdens in the world today. Although traditionally considered distinct pathological entities …