WNT signalling in prostate cancer

V Murillo-Garzón, R Kypta - Nature Reviews Urology, 2017 - nature.com
Genome sequencing and gene expression analyses of prostate tumours have highlighted
the potential importance of genetic and epigenetic changes observed in WNT signalling …

Nonantibiotic strategies for the prevention of infectious complications following prostate biopsy: a systematic review and meta-analysis

B Pradere, R Veeratterapillay… - The Journal of …, 2021 - auajournals.org
Purpose: We identify which nonantibiotic strategies could reduce the risk of infectious
complications following prostate biopsy. Materials and Methods: We performed a literature …

Darolutamide and survival in metastatic, hormone-sensitive prostate cancer

MR Smith, M Hussain, F Saad, K Fizazi… - … England Journal of …, 2022 - Mass Medical Soc
Background Darolutamide is a potent androgen-receptor inhibitor that has been associated
with increased overall survival among patients with nonmetastatic, castration-resistant …

Diagnostic Efficacy of 68Gallium-PSMA Positron Emission Tomography Compared to Conventional Imaging for Lymph Node Staging of 130 Consecutive Patients …

T Maurer, JE Gschwend, I Rauscher… - The Journal of …, 2016 - auajournals.org
Purpose: Current standard imaging techniques are insufficient to reliably detect lymph node
metastases in prostate cancer. Recently ligands of PSMA (prostate specific membrane …

Laparoscopic and robotic‐assisted versus open radical prostatectomy for the treatment of localised prostate cancer

D Ilic, SM Evans, CA Allan, JH Jung… - Cochrane Database …, 2017 - cochranelibrary.com
Background Prostate cancer is commonly diagnosed in men worldwide. Surgery, in the form
of radical prostatectomy, is one of the main forms of treatment for men with localised prostate …

Padeliporfin vascular-targeted photodynamic therapy versus active surveillance in men with low-risk prostate cancer (CLIN1001 PCM301): an open-label, phase 3 …

AR Azzouzi, S Vincendeau, E Barret, A Cicco… - The Lancet …, 2017 - thelancet.com
Background Vascular-targeted photodynamic therapy, a novel tissue-preserving treatment
for low-risk prostate cancer, has shown favourable safety and efficacy results in single-arm …

Quality of life outcomes after primary treatment for clinically localised prostate cancer: a systematic review

M Lardas, M Liew, RC van den Bergh, M De Santis… - European urology, 2017 - Elsevier
Context Current evidence-based management for clinically localised prostate cancer
includes active surveillance, surgery, external beam radiotherapy (EBRT) and …

Tumour genomic and microenvironmental heterogeneity for integrated prediction of 5-year biochemical recurrence of prostate cancer: a retrospective cohort study

E Lalonde, AS Ishkanian, J Sykes, M Fraser… - The lancet …, 2014 - thelancet.com
Background Clinical prognostic grou**s for localised prostate cancers are imprecise, with
30–50% of patients recurring after image-guided radiotherapy or radical prostatectomy. We …

Integration of copy number and transcriptomics provides risk stratification in prostate cancer: a discovery and validation cohort study

H Ross-Adams, AD Lamb, MJ Dunning, S Halim… - …, 2015 - thelancet.com
Background Understanding the heterogeneous genotypes and phenotypes of prostate
cancer is fundamental to improving the way we treat this disease. As yet, there are no …

177Lu-PSMA radioligand therapy for prostate cancer

WP Fendler, K Rahbar, K Herrmann… - Journal of Nuclear …, 2017 - Soc Nuclear Med
177Lu-prostate-specific membrane antigen (PSMA) radioligand therapy (RLT) using
inhibitors of PSMA is a novel therapeutic option in patients with metastatic castration …