The actomyosin cytoskeleton is responsible for most force-driven processes in cells and
tissues. How it assembles into the necessary structures at the right time and place is an …

Gametes undergo a specialized and reductional cell division termed meiosis. Female
gametes (oocytes) undergo two rounds of meiosis; the first meiotic division produces the …

Cells are filled with macromolecules and polymer networks that set scale-dependent viscous
and elastic properties to the cytoplasm. Although the role of these parameters in molecular …

Accurate chromosome segregation during meiosis is crucial for reproduction. Human and
porcine oocytes transiently cluster their chromosomes before the onset of spindle assembly …

Cytoskeletal networks of actin filaments and myosin motors drive many dynamic cell
processes. A key characteristic of these networks is their contractility. Despite intense …

The cytoskeleton–a collection of polymeric filaments, molecular motors, and crosslinkers–is
a foundational example of active matter, and in the cell assembles into organelles that guide …

Cytoplasm is a gel-like crowded environment composed of various macromolecules,
organelles, cytoskeletal networks, and cytosol. The structure of the cytoplasm is highly …

Constriction of the cytokinetic ring, a circular structure of actin filaments, is an essential step
during cell division. Mechanical forces driving the constriction are attributed to myosin motor …

Nuclear shape influences cell migration, gene expression and cell cycle progression, and is
altered in disease states like laminopathies and cancer. What factors and forces determine …

The molecular machinery of life is largely created via self-organisation of individual
molecules into functional assemblies. Minimal coarse-grained models, in which a whole …