Advanced theragnostics for the central nervous system (CNS) and neurological disorders using functional inorganic nanomaterials

B Conklin, BM Conley, Y Hou, M Chen… - Advanced Drug Delivery …, 2023 - Elsevier
Various types of inorganic nanomaterials are capable of diagnostic biomarker detection and
the therapeutic delivery of a disease or inflammatory modulating agent. Those multi …

Nanotechnology: new opportunities for the development of patch‐clamps

J Gao, C Liao, S Liu, T **a, G Jiang - Journal of nanobiotechnology, 2021 - Springer
The patch-clamp technique is one of the best approaches to investigate neural excitability.
Impressive improvements towards the automation of the patch-clamp technique have been …

Towards brain-tissue-like biomaterials

E Axpe, G Orive, K Franze, EA Appel - Nature Communications, 2020 - nature.com
Many biomaterials have been developed which aim to match the elastic modulus of the
brain for improved interfacing. However, other properties such as ultimate toughness, tensile …

The absence of AQP4/TRPV4 complex substantially reduces acute cytotoxic edema following ischemic injury

P Sucha, Z Hermanova, M Chmelova… - Frontiers in cellular …, 2022 - frontiersin.org
Introduction Astrocytic Aquaporin 4 (AQP4) and Transient receptor potential vanilloid 4
(TRPV4) channels form a functional complex that likely influences cell volume regulation …

Electroconductive and injectable hydrogels based on gelatin and PEDOT: PSS for a minimally invasive approach in nervous tissue regeneration

F Furlani, M Montanari, N Sangiorgi, E Saracino… - Biomaterials …, 2022 - pubs.rsc.org
This work describes the development of electroconductive hydrogels as injectable matrices
for neural tissue regeneration by exploiting a biocompatible conductive polymer–poly (3, 4 …

Nanoparticle and biomolecule surface modification synergistically increases neural electrode recording yield and minimizes inflammatory host response

KM Woeppel, XT Cui - Advanced healthcare materials, 2021 - Wiley Online Library
Due to their ability to interface with neural tissues, neural electrodes are the key tool used for
neurophysiological studies, electrochemical detection, brain computer interfacing, and …

Structural and functional properties of astrocytes on PCL based electrospun fibres

E Saracino, V Cirillo, M Marrese, V Guarino… - Materials Science and …, 2021 - Elsevier
Increasing evidences are demonstrating that structural and functional properties of non-
neuronal brain cells, called astrocytes, such as those of cytoskeleton and of ion channels …

Nano-hybrid electrospun non-woven mats made of wool keratin and hydrotalcites as potential bio-active wound dressings

D Giuri, M Barbalinardo, G Sotgiu, R Zamboni… - Nanoscale, 2019 - pubs.rsc.org
In this work, nano-hybrid electrospun non-woven mats made of wool keratin combined with
diclofenac loaded hydrotalcites (HTD) were prepared and characterized as potential drug …

Neuro‐nano interfaces: utilizing nano‐coatings and nanoparticles to enable next‐generation electrophysiological recording, neural stimulation, and biochemical …

AT Young, N Cornwell… - Advanced functional …, 2018 - Wiley Online Library
Neural interfaces provide a window into the workings of the nervous system—enabling both
biosignal recording and modulation. Traditionally, neural interfaces have been restricted to …

Graphene oxide upregulates the homeostatic functions of primary astrocytes and modulates astrocyte-to-neuron communication

M Chiacchiaretta, M Bramini, A Rocchi, A Armirotti… - Nano …, 2018 - ACS Publications
Graphene-based materials are the focus of intense research efforts to devise novel
theranostic strategies for targeting the central nervous system. In this work, we have …