Developmental trajectories of early life stress and trauma: a narrative review on neurobiological aspects beyond stress system dysregulation

A Agorastos, P Pervanidou, GP Chrousos… - Frontiers in …, 2019 - frontiersin.org
Early life stressors display a high universal prevalence and constitute a major public health
problem. Prolonged psychoneurobiological alterations as sequelae of early life stress (ELS) …

Childhood and adolescent adversity and cardiometabolic outcomes: a scientific statement from the American Heart Association

SF Suglia, KC Koenen, R Boynton-Jarrett, PS Chan… - Circulation, 2018 - ahajournals.org
Adverse experiences in childhood and adolescence, defined as subjectively perceived
threats to the safety or security of the child's bodily integrity, family, or social structures, are …

Health effects associated with exposure to intimate partner violence against women and childhood sexual abuse: a burden of proof study

CN Spencer, M Khalil, M Herbert, AY Aravkin… - Nature medicine, 2023 - nature.com
The health impacts of intimate partner violence against women and childhood sexual abuse
are not fully understood. Here we conducted a systematic review by comprehensively …

Childhood trauma and adulthood inflammation: a meta-analysis of peripheral C-reactive protein, interleukin-6 and tumour necrosis factor-α

D Baumeister, R Akhtar, S Ciufolini, CM Pariante… - Molecular …, 2016 - nature.com
Childhood trauma confers higher risk of adulthood physical and mental illness; however, the
biological mechanism mediating this association remains largely unknown. Recent research …

The long-term health consequences of child physical abuse, emotional abuse, and neglect: a systematic review and meta-analysis

RE Norman, M Byambaa, R De, A Butchart… - PLoS …, 2012 - journals.plos.org
Background Child sexual abuse is considered a modifiable risk factor for mental disorders
across the life course. However the long-term consequences of other forms of child …

Sex differences in cardiovascular disease–impact on care and outcomes

KH Humphries, M Izadnegahdar, T Sedlak… - Frontiers in …, 2017 - Elsevier
Globally, cardiovascular disease (CVD) is the number one killer of women; one third of
female deaths are due to ischemic heart disease and stroke (WHO, 2013). Historically …

Adverse childhood experiences are associated with adult sleep disorders: a systematic review

S Kajeepeta, B Gelaye, CL Jackson, MA Williams - Sleep medicine, 2015 - Elsevier
Adverse childhood experiences (ACEs) represent substantial threats to public health and
affect about 58% of youth in the US. In addition to their acute effects such as injury and …

Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults: The Adverse Childhood Experiences (ACE) Study

VJ Felitti, RF Anda, D Nordenberg… - American journal of …, 1998 - Elsevier
Background: The relationship of health risk behavior and disease in adulthood to the
breadth of exposure to childhood emotional, physical, or sexual abuse, and household …

[PDF][PDF] Child abuse and physical health in adulthood

TO Afifi, HL MacMillan, M Boyle, K Cheung, T Taillieu… - 2016 - researchgate.net
Background: A large literature exists on the association between child abuse and mental
health, but less is known about associations with physical health. The study objective was to …

A prospective investigation of physical health outcomes in abused and neglected children: New findings from a 30-year follow-up

CS Widom, SJ Czaja, T Bentley… - American journal of …, 2012 - ajph.aphapublications.org
Objectives. We investigated whether abused and neglected children are at risk for negative
physical health outcomes in adulthood. Methods. Using a prospective cohort design, we …