Saponin surfactants used in drug delivery systems: A new application for natural medicine components

Y Liao, Z Li, Q Zhou, M Sheng, Q Qu, Y Shi… - International journal of …, 2021 - Elsevier
Saponins are a group of compounds widely distributed in the plant kingdom. Due to their
amphiphilic characteristic structure, saponins have high surface activity and self-assembly …

Glycyrrhizic acid as a multifunctional drug carrier–From physicochemical properties to biomedical applications: A modern insight on the ancient drug

OY Selyutina, NE Polyakov - International journal of pharmaceutics, 2019 - Elsevier
Glycyrrhizic acid is the main active component of Licorice root which has been known in
traditional Chinese and Japanese medicine since ancient times. In these cultures …

[HTML][HTML] Synergistic mechanisms of constituents in herbal extracts during intestinal absorption: Focus on natural occurring nanoparticles

Q Zhao, X Luan, M Zheng, XH Tian, J Zhao, WD Zhang… - Pharmaceutics, 2020 - mdpi.com
The systematic separation strategy has long and widely been applied in the research and
development of herbal medicines. However, the pharmacological effects of many bioactive …

The colorful world of carotenoids: A profound insight on therapeutics and recent trends in nano delivery systems

S Maghsoudi, B Taghavi Shahraki… - Critical reviews in …, 2022 - Taylor & Francis
The therapeutic effects of carotenoids as dietary supplements to control or even treat some
specific diseases including diabetic retinopathy, cardiovascular diseases, bacterial …

Constituents, Pharmacokinetics, and Pharmacology of Gegen-Qinlian Decoction

JZ Lu, D Ye, BL Ma - Frontiers in pharmacology, 2021 - frontiersin.org
Gegen-Qinlian decoction (GQD) is a classic traditional Chinese medicine (TCM) formula. It is
composed of four TCMs, including Puerariae Lobatae Radix, Scutellariae Radix, Coptidis …

Edible pentacyclic triterpenes: A review of their sources, bioactivities, bioavailability, self-assembly behavior, and emerging applications as functional delivery vehicles

S Liu, H Liu, L Zhang, C Ma… - Critical Reviews in Food …, 2024 - Taylor & Francis
Edible pentacyclic triterpenes (PTs) are a group of nutraceutical ingredients commonly
distributed in human diets. Existing evidence has proven that they have various biological …

Supramolecular carotenoid complexes of enhanced solubility and stability—The way of bioavailability improvement

AL Focsan, NE Polyakov, LD Kispert - Molecules, 2019 - mdpi.com
Carotenoids are natural dyes and antioxidants widely used in food processing and in
therapeutic formulations. However, their practical application is restricted by their high …

Recent advances in glycyrrhizin metabolism, health benefits, clinical effects and drug delivery systems for efficacy improvement; a comprehensive review

AF Bakr, P Shao, MA Farag - Phytomedicine, 2022 - Elsevier
Background Glycyrrhizin (GL) is a major active constituent of licorice root (Glycyrrhiza
glabra) that is considered one of the oldest and most frequently employed botanicals in …

Preparation of astaxanthin micelles self-assembled by a mechanochemical method from hydroxypropyl β-cyclodextrin and glyceryl monostearate with enhanced …

W Su, NE Polyakov, W Xu, W Su - International Journal of Pharmaceutics, 2021 - Elsevier
This research aimed to overcome the current challenges in the application of natural
carotenoid antioxidants, such as their complex preparation processes, low bioavailability …

Disodium salt of glycyrrhizic acid–A novel supramolecular delivery system for anthelmintic drug praziquantel

ES Meteleva, YS Chistyachenko, LP Suntsova… - Journal of Drug Delivery …, 2019 - Elsevier
The aim of the study was to enhance the solubility and bioavailability of praziquantel (PZQ)
through mechanochemical preparation of its solid compositions with the disodium salt of …