Reviewed herein is the aromatic Cope rearrangement, a Cope rearrangement where one
(or both) of the alkenes of the 1, 5-diene are part of a greater aromatic system. While the …

The catalytic diastereodivergent construction of stereoisomers having two or more
stereogenic centers has been extensively studied. In contrast, the switchable introduction of …

A general protocol for the preparation of enantioenriched α-tetrasubstituted α-trifluoromethyl
homoallylic amines is disclosed. Despite the significant challenge in stereoselectivity …

The development of an iridium catalyzed enantioselective α-alkylation of azlactones has
been described. The reaction provides rapid access to a wide range of enantio-enriched …

An asymmetric allylic alkylation/Cope rearrangement (AAA/[3, 3]) capable of
stereoselectively constructing vicinal stereocenters has been developed. Strategically …

Dicyanoalkenes are versatile reagents in organic synthesis and they have been extensively
used in a wide variety of organic transformations. However, their reactivity towards …

This is a review of papers published in the year 2018 that focus on the synthesis, reactivity,
or properties of compounds containing a carbon-transition metal double or triple bond …

In this paper, micellar-mediated synthesis of chalcones was explored. After optimization of
the reaction conditions, the cationic surfactant CTAB and the nonionic one, Tween 80, were …

Reported herein is the discovery of a diastereoselective indole-dearomative Cope
rearrangement. A suite of minor driving forces promote dearomatization:(i) steric congestion …

Herein described is a strategy for promoting thermodynamically unfavorable [3, 3] Cope
rearrangements. 3, 3-Dicyano-1, 5-dienes that are resistant to the thermal rearrangement …