Ferritin self-assembly, structure, function, and biotechnological applications
VV Sudarev, SM Dolotova, SM Bukhalovich… - International journal of …, 2023 - Elsevier
Ferritin is a vital protein complex responsible for storing iron in almost all living organisms. It
plays a crucial role in various metabolic pathways, inflammation processes, stress response …
plays a crucial role in various metabolic pathways, inflammation processes, stress response …
Prospects of using protein engineering for selective drug delivery into a specific compartment of target cells
A large number of proteins are successfully used to treat various diseases. These include
natural polypeptide hormones, their synthetic analogues, antibodies, antibody mimetics …
natural polypeptide hormones, their synthetic analogues, antibodies, antibody mimetics …
Methionine gamma lyase fused with S3 domain VGF forms octamers and adheres to tumor cells via binding to EGFR
Methods for targeting enzymes exhibiting anticancer properties, such as methionine γ-lyase
(MGL), have not yet been sufficiently developed. Here, we present the data describing the …
(MGL), have not yet been sufficiently developed. Here, we present the data describing the …
Structural insights into 3Fe–4S ferredoxins diversity in M. tuberculosis highlighted by a first redox complex with P450
Ferredoxins are small iron–sulfur proteins and key players in essential metabolic pathways.
Among all types, 3Fe–4S ferredoxins are less studied mostly due to anaerobic requirements …
Among all types, 3Fe–4S ferredoxins are less studied mostly due to anaerobic requirements …
[HTML][HTML] The Delivery of biologically active agents into the nuclei of target cells for the purposes of translational medicine
AS Sobolev - Acta Naturae (англоязычная версия), 2020 - cyberleninka.ru
Development of vehicles for the subcellular targeted delivery of biologically active agents is
very promising for the purposes of translational medicine. This review summarizes the …
very promising for the purposes of translational medicine. This review summarizes the …
Modular nanotransporters capable of binding to SARS-CoV-2 virus nucleocapsid protein in target cells
YV Khramtsov, AV Ulasov, TN Lupanova… - Doklady Biochemistry …, 2023 - Springer
On the basis of literature data, an antibody-like molecule, monobody, was selected that is
capable of interacting with the nucleocapsid protein (N protein) of the SARS-CoV-2 virus …
capable of interacting with the nucleocapsid protein (N protein) of the SARS-CoV-2 virus …
[HTML][HTML] Anti-Stokes fluorescence excitation reveals conformational mobility of the C-phycocyanin chromophores
GV Tsoraev, EA Protasova, EA Klimanova… - Structural …, 2022 - pubs.aip.org
The structural organization of natural pigment-protein complexes provides a specific
environment for the chromophore groups. Yet, proteins are inherently dynamic and …
environment for the chromophore groups. Yet, proteins are inherently dynamic and …
Modular Nanotransporters Delivering Biologically Active Molecules to the Surface of Mitochondria
Treatment of various diseases, in particular cancer, usually requires the targeting of
biologically active molecules at a selected subcellular compartment. We modified our …
biologically active molecules at a selected subcellular compartment. We modified our …
The Possibilities of Studying Biological Objects on a Pulsed Reactor
Small-angle scattering makes it possible to solve structural biology problems without special
sample preparation, which is typical for such methods as X-ray diffraction on protein crystals …
sample preparation, which is typical for such methods as X-ray diffraction on protein crystals …
Selection of an amino acid site with one of the fastest cleavage kinetics by the endosomal protease cathepsin B for potential use in drug delivery systems
YV Khramtsov, GP Georgiev, AS Sobolev - Doklady Biochemistry and …, 2023 - Springer
On the basis of known published data, six peptide sequences were selected that are
potentially capable of being rapidly cleaved by the endosomal protease cathepsin B. For …
potentially capable of being rapidly cleaved by the endosomal protease cathepsin B. For …