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Cyanobacteria—From the oceans to the potential biotechnological and biomedical applications
Cyanobacteria are photosynthetic prokaryotic organisms which represent a significant
source of novel, bioactive, secondary metabolites, and they are also considered an …
source of novel, bioactive, secondary metabolites, and they are also considered an …
Developments of cyanobacteria for nano-marine drugs: Relevance of nanoformulations in cancer therapies
Current trends in the application of nanomaterials are emerging in the nano-
biotechnological sector for development of medicines. Cyanobacteria (blue-green algae) …
biotechnological sector for development of medicines. Cyanobacteria (blue-green algae) …
Design, synthesis and evaluation of new quinazolin-4-one derivatives as apoptotic enhancers and autophagy inhibitors with potent antitumor activity
HSA ElZahabi, MS Nafie, D Osman… - European Journal of …, 2021 - Elsevier
This work presents the design and synthesis of a series of new quinazolin-4-one derivatives,
based on the established effectiveness of quinazoline-based small molecules as anticancer …
based on the established effectiveness of quinazoline-based small molecules as anticancer …
Drug design strategies with metal-hydroxyquinoline complexes
Introduction: 8-hydroxyquinoline derivatives and their complexes with transition metals are
the subject of many studies due to their anticancer, anti-inflammatory, anti-infective, and …
the subject of many studies due to their anticancer, anti-inflammatory, anti-infective, and …
Caenorhabditis elegans as an Infection Model for Pathogenic Mold and Dimorphic Fungi: Applications and Challenges
The threat burden from pathogenic fungi is universal and increasing with alarming high
mortality and morbidity rates from invasive fungal infections. Understanding the virulence …
mortality and morbidity rates from invasive fungal infections. Understanding the virulence …
Molecular target interactions of quinoline derivatives as anticancer agents: A review
One of the leading causes of death worldwide is cancer, which poses substantial risks to
both society and an individual's life. Cancer therapy is still challenging, despite …
both society and an individual's life. Cancer therapy is still challenging, despite …
Discovery of a novel dibromoquinoline compound exhibiting potent antifungal and antivirulence activity that targets metal ion homeostasis
H Mohammad, NH Elghazawy… - ACS infectious …, 2018 - ACS Publications
Globally, invasive fungal infections pose a significant challenge to modern human medicine
due to the limited number of antifungal drugs and the rise in resistance to current antifungal …
due to the limited number of antifungal drugs and the rise in resistance to current antifungal …
Quinoline and ferrocene conjugates: Synthesis, computational study and biological evaluations
Novel O‐alkylated quinoline and N‐alkylated 4‐quinolone derivatives attached to the
ferrocene moiety through 4, 1‐(7a–d, 8a–d and 12a–d) and 1, 4‐disubstituted (9a, 9b, 10a …
ferrocene moiety through 4, 1‐(7a–d, 8a–d and 12a–d) and 1, 4‐disubstituted (9a, 9b, 10a …
Anticancer Activity–Structure Relationship of Quinolinone-Core Compounds: An Overall Review
HK Beker, I Yıldırım - Pharmaceutical Chemistry Journal, 2023 - Springer
Quinolinone/quinoline is one of the most unique structures in the discovery of heterocycles
that have attracted much attention in the field of medicinal chemistry. The basic scaffold of …
that have attracted much attention in the field of medicinal chemistry. The basic scaffold of …
Exploring quinolone scaffold: Unravelling the chemistry of anticancer drug design
Globally, cancer is considered as the major leading cause in burdening the patient's health
care system globally. The growing threat of drug-resistant cancers renders an urgent need to …
care system globally. The growing threat of drug-resistant cancers renders an urgent need to …